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南非寻求治疗的物质使用障碍和共患注意缺陷/多动障碍患者的流行情况和特征。

Prevalence and characteristics of South African treatment-seeking patients with substance use disorder and co-occurring attention-deficit/hyperactivity disorder.

机构信息

Drug Utilization Research Unit (DURU), Department of Pharmacy, Nelson Mandela University , Port Elizabeth, South Africa.

University of Limpopo , Sovenga, South Africa.

出版信息

Expert Rev Clin Pharmacol. 2020 Nov;13(11):1271-1280. doi: 10.1080/17512433.2020.1835467. Epub 2020 Oct 22.

DOI:10.1080/17512433.2020.1835467
PMID:33040639
Abstract

BACKGROUND

Attention-Deficit/Hyperactivity Disorder (ADHD) constitutes a significant risk factor for the development of Substance Use Disorders (SUDs). Individuals with both conditions use more substances, and the pattern of substance use seems to differ between individuals with and without ADHD.

RESEARCH AIM AND OBJECTIVES

To establish the prevalence of ADHD symptoms in adult South African treatment-seeking patients with SUD, and the pattern of substance use and presence of previous ADHD diagnoses and pharmacotherapy.

METHODS

Adult patients (N = 360) were recruited from rehabilitation facilities and screened using the ADHD Self-Report Scale Symptom Checklist (ASRS-v1.1). Questions included demographics, substance consumption and current/historical use of ADHD-indicated medication.

RESULTS

A third (36.0%) of patients with SUD screened positive for ADHD - 14.6% had been diagnosed with ADHD prior to admission, and indicated pharmacotherapy, while 68.5% of those screened positive were not hitherto diagnosed with ADHD (p < 0.001). A statistical difference was found for polysubstance use with the ADHD group significantly being treated more frequently for use of more than one substance (p = 0.04).

CONCLUSIONS AND IMPLICATIONS

High rates of untreated and unrecognized ADHD were found among treatment-seeking SUD patients. Preventative strategies are crucial to reduce substance use and the development of SUD in individuals affected by ADHD.

摘要

背景

注意力缺陷多动障碍(ADHD)是物质使用障碍(SUD)发展的一个重要危险因素。患有这两种疾病的人会使用更多的物质,而且ADHD 患者和非 ADHA 患者的物质使用模式似乎不同。

研究目的和目标

确定患有 SUD 的南非成年治疗寻求者中 ADHD 症状的患病率,以及物质使用模式以及以前的 ADHD 诊断和药物治疗的存在情况。

方法

从康复设施中招募成年患者(N=360),并使用 ADHD 自我报告量表症状清单(ASRS-v1.1)进行筛查。问题包括人口统计学、物质消费以及当前/历史上使用 ADHD 指征药物的情况。

结果

三分之一(36.0%)的 SUD 患者对 ADHD 呈阳性反应——14.6%在入院前被诊断为 ADHD,并接受了药物治疗,而 68.5%的阳性筛查者以前未被诊断为 ADHD(p<0.001)。对多种物质使用进行了统计学差异分析,ADHD 组的治疗频率明显更高,因为他们使用了一种以上的物质(p=0.04)。

结论和意义

在寻求治疗的 SUD 患者中,发现未治疗和未被识别的 ADHD 发生率很高。预防策略对于减少 ADHD 患者的物质使用和 SUD 的发展至关重要。

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