Department of Neurology, Massachusetts General Hospital, 55 Fruit Street WACC 721G, Boston, Massachusetts 02114, USA; Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston MA 02115, USA.
Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Kirstein 406D, Boston, MA 02215, USA.
Neurol Clin. 2020 Nov;38(4):983-996. doi: 10.1016/j.ncl.2020.08.005.
Substance use disorders-and their associated neurologic complications-are frequently encountered by neurologists as well as emergency room physicians, internists, psychiatrists, and medical intensivists. Prominent neurologic sequelae of drug abuse, such as seizure and stroke, are common and often result in patients receiving medical attention. However, less overt neurologic manifestations, such as dysautonomia and perceptual disturbances, may be initially misattributed to primary medical or psychiatric illness, respectively. This article focuses on the epidemiology, pharmacology, and complications associated with commonly used recreational drugs, including opioids, alcohol, marijuana, cocaine, and hallucinogens.
物质使用障碍及其相关的神经系统并发症经常被神经内科医生、急诊医生、内科医生、精神科医生和重症监护医生遇到。药物滥用的突出神经后遗症，如癫痫发作和中风，很常见，经常导致患者接受医疗关注。然而，不太明显的神经表现，如自主神经功能紊乱和感知障碍，可能最初分别归因于原发性医学或精神疾病。本文重点介绍了常见的娱乐性药物（包括阿片类药物、酒精、大麻、可卡因和致幻剂）的流行病学、药理学和并发症。
