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用于治疗肝细胞癌的特定中草药的抗癌特性。

Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment.

作者信息

Ping Zang, Jun Xue, Yan Wang, Jun Zhang

机构信息

Pharmacy, Qingdao Island Central Hospital.

Department of Pharmacy, Huangdao district Chinese Medicine Hospital, Qingdao.

出版信息

Eur J Integr Med. 2020 Oct 3:101215. doi: 10.1016/j.eujim.2020.101215.

DOI:10.1016/j.eujim.2020.101215
PMID:33042292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7532350/
Abstract

AIMS

This essay explores the anti-cancer activity of specific Chinese herbal medicines to clarify how effective Chinese herbal medicine is used for handling hepatocellular carcinoma.

METHODS

Literature form publica domain were studied and an analysis of anti-cancer activity of specific Chinese herbal medicines is presented in this review.

RESULTS

Hepatocellular carcinoma is one of the most dangerous malignant tumors in the world. The operative diagnosis of liver cancer remains a significant challenge. Although surgery tissue resection is encouraging, a high risk of recurrence and metastasis, illustrating disease-related mortality is desperately required to enhance postoperative preventive and therapeutic clinical procedures. The almost only effective clinical intervention seems to be developing advanced targeted therapies such as sorafenib for hepatocellular carcinoma patients, but there is little research in this field. Because their preventative/therapeutic properties strengthen Chinese herbal medicinal compounds, they are deemed relevant to the treatment of hepatocellular carcinoma. Conclusion: Chinese herbal medicine derivates provide multifaceted, orientated and orchestrated therapy, making it an ideal candidate for inhibiting hepatocellular tumor production and metastasis.

摘要

目的

本文探讨特定中草药的抗癌活性,以阐明中草药在治疗肝细胞癌方面的有效性。

方法

研究了来自公共领域的文献,并在本综述中对特定中草药的抗癌活性进行了分析。

结果

肝细胞癌是世界上最危险的恶性肿瘤之一。肝癌的手术诊断仍然是一项重大挑战。尽管手术组织切除令人鼓舞,但复发和转移风险很高,迫切需要提高术后预防和治疗的临床程序以降低疾病相关死亡率。几乎唯一有效的临床干预似乎是为肝细胞癌患者开发先进的靶向治疗药物,如索拉非尼,但该领域的研究很少。由于其预防/治疗特性增强了中草药化合物的作用,它们被认为与肝细胞癌的治疗相关。结论:中草药衍生物提供多方面、有针对性和精心安排的治疗,使其成为抑制肝细胞肿瘤产生和转移的理想选择。

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Research Progress of Glycyrrhizic Acid on Antiviral Activity.甘草酸抗病毒活性的研究进展。
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Role of nonresolving inflammation in hepatocellular carcinoma development and progression.持续性炎症在肝细胞癌发生发展中的作用。
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Isolates from Alpinia officinarum Hance attenuate LPS-induced inflammation in HepG2: Evidence from in silico and in vitro studies.从高良姜中分离得到的化合物能够减轻 LPS 诱导的 HepG2 细胞炎症反应:来自计算机模拟和体外研究的证据。
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Recent advances on the anti-cancer properties of Nigella sativa, a widely used food additive.广泛使用的食品添加剂黑种草籽抗癌特性的最新进展。
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