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微波辐照固定大鼠脑内糖原的区域分布。

The regional distribution of glycogen in rat brain fixed by microwave irradiation.

作者信息

Sagar S M, Sharp F R, Swanson R A

出版信息

Brain Res. 1987 Aug 4;417(1):172-4. doi: 10.1016/0006-8993(87)90195-8.

Abstract

Glycogen concentrations were measured by fluorescence enzymatic assay in rat brains fixed by focused microwave irradiation Regional glycogen concentrations varied 2.5 fold, ranging from 27.1 nmol glucosyl units/mg protein in the striatum to 52.3 nmol/mg protein in the cerebellum and 69.9 nmol/mg protein in the pons-medulla; other regions were intermediate in concentration. Since glycogen is contained primarily within astrocytes, this regional variation may reflect regional differences in astrocyte energy metabolism.

摘要

通过荧光酶法测定聚焦微波辐射固定的大鼠脑中的糖原浓度。区域糖原浓度变化2.5倍,范围从纹状体中的27.1 nmol葡萄糖基单位/毫克蛋白质到小脑中的52.3 nmol/毫克蛋白质以及脑桥-延髓中的69.9 nmol/毫克蛋白质;其他区域浓度处于中间水平。由于糖原主要存在于星形胶质细胞内,这种区域差异可能反映了星形胶质细胞能量代谢的区域差异。

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