使用体外系统的致畸学研究。II. 啮齿动物肢体芽培养系统。
Teratological research using in vitro systems. II. Rodent limb bud culture system.
作者信息
Friedman L
出版信息
Environ Health Perspect. 1987 Jun;72:211-9. doi: 10.1289/ehp.8772211.
Abstract
This review represents a compilation of information related to the rodent limb bud culture system from approximately 80 publications after 1969 and conversations with workers in the field. Most of these papers and book chapters refer exclusively to studies with the mouse limb bud. Sections in this review include historical review, end point measurements, activating systems, types of compounds studied and dose response, reproducibility, statistical analysis, equipment and personnel requirements, mechanisms, and summary.
摘要
本综述汇集了1969年以后约80篇出版物中与啮齿动物肢芽培养系统相关的信息，以及与该领域研究人员的交流内容。这些论文和书籍章节大多专门涉及小鼠肢芽的研究。本综述的章节包括历史回顾、终点测量、激活系统、所研究化合物的类型和剂量反应、可重复性、统计分析、设备和人员要求、作用机制以及总结。
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Environ Health Perspect. 1987 Jun;72:211-9. doi: 10.1289/ehp.8772211.
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本文引用的文献
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A modified technique for organ culture in vitro.一种改良的体外器官培养技术。
Exp Cell Res. 1954 Feb;6(1):246-8. doi: 10.1016/0014-4827(54)90169-x.
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Significance of organ culture techniques for evaluation of prenatal toxicity.器官培养技术在评估产前毒性中的意义。
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4
Bioactivation of thalidomide by a monkey liver fraction in a rat limb culture system.沙利度胺在大鼠肢体培养系统中被猴肝组分生物活化。
Prog Clin Biol Res. 1983;110 Pt A:377-85.
5
[General effects of cytosine arabinoside on the embryo of reptiles].[阿糖胞苷对爬行动物胚胎的一般影响]
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6
Fish and amphibian embryos--a model system for evaluating teratogenicity.鱼类和两栖类胚胎——一种用于评估致畸性的模型系统。
Fundam Appl Toxicol. 1983 Jul-Aug;3(4):237-42. doi: 10.1016/s0272-0590(83)80134-1.
7
Limb development in mouse embryos. III. Cellular events underlying the determination of altered skeletal patterns following treatment with 5'fluoro-2-deoxyuridine.小鼠胚胎肢体发育。III. 5'-氟-2-脱氧尿苷处理后骨骼模式改变的决定过程中的细胞事件。
Teratology. 1981 Apr;23(2):241-51. doi: 10.1002/tera.1420230209.
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Effect of thalidomide-derivatives on limb development in culture.沙利度胺衍生物对体外培养肢体发育的影响。
Prog Clin Biol Res. 1983;110 Pt A:387-97.
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Biochem Pharmacol. 1983 Oct 1;32(19):2881-90. doi: 10.1016/0006-2952(83)90392-1.
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