Sørensen F B, Paulsen S M
Histopathology. 1987 Aug;11(8):857-69. doi: 10.1111/j.1365-2559.1987.tb01889.x.
The light microscopic, immunohistochemical and ultrastructural features of a clear cell carcinoma of the breast have been studied. Both intraductal and invasive components were found. Histochemistry showed large amounts of intracytoplasmic glycogen and sparse neutral mucin in the tumour. The tumour cells were stained by antisera to carcinoembryonic antigen, keratin and epithelial membrane antigen, but not by antisera to alpha-lactalbumin, desmin or vimentin. Ultrastructurally, the epithelial derivation of the tumour was confirmed. Only a few intracytoplasmic lumina were demonstrated. The tumour was classified as a mucin-containing variant of glycogen-rich, clear cell carcinoma of the breast.
对一例乳腺透明细胞癌的光镜、免疫组化及超微结构特征进行了研究。发现了导管内和浸润性成分。组织化学显示肿瘤细胞内有大量胞质糖原和少量中性黏液。肿瘤细胞被癌胚抗原、角蛋白和上皮膜抗原的抗血清染色，但未被α-乳白蛋白、结蛋白或波形蛋白的抗血清染色。超微结构证实了肿瘤的上皮来源。仅见少数胞质内小管。该肿瘤被分类为富含糖原的乳腺透明细胞癌的含黏液变体。
