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从中医角度看:新冠康复者精神障碍的治疗

From the perspective of Traditional Chinese Medicine: Treatment of mental disorders in COVID-19 survivors.

作者信息

Ma Ke, Wang Xin, Feng Shiyao, Xia Xueshan, Zhang Hongxiu, Rahaman Abdul, Dong Zhenfei, Lu Yanting, Li Xiuyang, Zhou Xiaoyu, Zhao Haijun, Wang Yuan, Wang Shijun, Baloch Zulqarnain

机构信息

College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.

College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.

出版信息

Biomed Pharmacother. 2020 Dec;132:110810. doi: 10.1016/j.biopha.2020.110810. Epub 2020 Sep 30.

Abstract

PURPOSE

The aim of this study is to explore the possible benefits of traditional Chinese medicine on the pathogenesis of psychological and mental health of COVID-19 survivors.

METHODS

A literature search was conducted to confirm the effects of COVID-19 on psychological and mental health of survivors. In addition to this, on the basis of signs and symptoms, TCM were used on treat mental disorder as per suggested clinical and animal experimental data plus relevant records in classical Chinese medicine books written by Zhang Zhongiing during Han Dynasty. A series of treatment plans were prescribed for COVID-19 survivors with psychological and mental disorders.

RESULTS

According to previous extensive studies focusing on effects on mental health of survivors, high incidence was observed in severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) survivors. During investigations of mental health of COVID-19 patients and survivors, it is observed that they also had symptoms of mental disorders and immune dysfunction. Furthermore, it was also proposed that depression, anxiety and post-traumatic stress disorder (PTSD) were most common mental disorders requiring special attention after the recovery from COVID-19. The symptoms of COVID-19 were analyzed, and the TCM syndrome of the depression, anxiety and PTSD after recovered from COVID19 was interpreted as internal heat and Yin deficiency. These three mental disorders pertains the category of "Lily disease", "hysteria" and "deficient dysphoria" in TCM.

CONCLUSION

Lily Bulb, Rhizoma Anemarrhena Decoction and Ganmai Dazao Decoction were used to treat depression. Suanzaoren Decoction, Huanglian Ejiao Decoction and Zhizi Chi Decoction were suggested for anxiety. Moreover, Lily Bulb, Rehmannia Decoction and Guilu Erxian Decoction were the formula for PTSD.

摘要

目的

本研究旨在探讨中医对新型冠状病毒肺炎康复者心理和心理健康发病机制的潜在益处。

方法

进行文献检索以确认新型冠状病毒肺炎对康复者心理和心理健康的影响。除此之外,根据症状体征,依据临床和动物实验数据以及汉代张仲景所著中医典籍中的相关记载,运用中医方法治疗精神障碍。为患有心理和精神障碍的新型冠状病毒肺炎康复者制定了一系列治疗方案。

结果

根据以往对康复者心理健康影响的广泛研究,在严重急性呼吸综合征(SARS)和中东呼吸综合征(MERS)康复者中观察到高发病率。在对新型冠状病毒肺炎患者和康复者的心理健康调查中,发现他们也有精神障碍和免疫功能障碍的症状。此外,还提出抑郁、焦虑和创伤后应激障碍(PTSD)是新型冠状病毒肺炎康复后最常见的需要特别关注的精神障碍。分析了新型冠状病毒肺炎的症状,并将新型冠状病毒肺炎康复后抑郁、焦虑和创伤后应激障碍的中医证候解释为内热阴虚。这三种精神障碍属于中医“百合病”“癔症”和“虚烦”范畴。

结论

百合知母汤、黄连阿胶汤和栀子豉汤用于治疗抑郁。酸枣仁汤、黄连阿胶汤和栀子豉汤用于治疗焦虑。此外,百合地黄汤、归脾汤和龟鹿二仙胶汤是治疗创伤后应激障碍的方剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ad2/7524684/7e41a4c77d35/gr1_lrg.jpg

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