Su Tao, Han Mei, Cao Dan, Xu Mingyue
Co-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Nanjing Forestry University, Nanjing 210037, China.
Key Laboratory of State Forestry Administration on Subtropical Forest Biodiversity Conservation, Nanjing Forestry University, Nanjing 210037, China.
J Fungi (Basel). 2020 Oct 12;6(4):220. doi: 10.3390/jof6040220.
Plant host defense peptides (HDPs), also known as antimicrobial peptides (AMPs), are regarded as one of the most prevalent barriers elaborated by plants to combat various infective agents. Among the multiple classes of HDPs, the Snakin class attracts special concern, as they carry 12 cysteine residues, being the foremost cysteine-rich peptides of the plant HDPs. Also, their cysteines are present at very highly conserved positions and arranged in an extremely similar way among different members. Like other plant HDPs, Snakins have been shown to exhibit strong antifungal and antibacterial activity against a wide range of plant pathogens. Moreover, they display diversified biological activities in many aspects of plant growth and the development process. This review is devoted to present the general characters of the Snakin class of plant HDPs, as well as the individual features of different Snakin family members. Specifically, the sequence properties, spatial structures, distributions, expression patterns and biological activities of Snakins are described. In addition, further detailed classification of the Snakin family members, along with their possible mode of action and potential applications in the field of agronomy and pathology are discussed.
植物宿主防御肽（HDPs），也被称为抗菌肽（AMPs），被认为是植物构建的对抗各种感染因子的最普遍屏障之一。在多种类型的HDPs中，蛇形肽类引起了特别关注，因为它们含有12个半胱氨酸残基，是植物HDPs中最主要的富含半胱氨酸的肽。此外，它们的半胱氨酸位于非常保守的位置，并且在不同成员之间以极其相似的方式排列。与其他植物HDPs一样，蛇形肽已被证明对多种植物病原体具有强大的抗真菌和抗菌活性。此外，它们在植物生长和发育过程的许多方面表现出多样化的生物活性。本综述致力于介绍植物HDPs蛇形肽类的一般特征，以及不同蛇形肽家族成员的个体特征。具体而言，描述了蛇形肽的序列特性、空间结构、分布、表达模式和生物活性。此外，还讨论了蛇形肽家族成员的进一步详细分类，以及它们可能的作用方式和在农学和病理学领域的潜在应用。
