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亚急性曲霉病“真菌球”并发新型冠状病毒肺炎

Subacute Aspergillosis "Fungal Balls" Complicating COVID-19.

作者信息

Patti Ravi Karan, Dalsania Nishil R, Somal Navjot, Sinha Ankur, Mehta Sanwal, Ghitan Monica, Seneviratne Chanaka, Kupfer Yizhak

机构信息

Maimonides Medical Center, Brooklyn, NY, USA.

出版信息

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620966475. doi: 10.1177/2324709620966475.

Abstract

Severe acute respiratory syndrome coronavirus-2 infection (SARS-CoV-2), commonly known as COVID-19 (coronavirus disease-2019), began in the Wuhan District of Hubei Province, China. It is regarded as one of the worst pandemics, which has consumed both human lives and the world economy. COVID-19 infection mainly affects the lungs triggering severe hypoxemic respiratory failure, also providing a nidus for superimposed bacterial and fungal infections. We report the case of a 73-year-old male who presented with progressive dyspnea; diagnosed with SARS-CoV-2-related severe acute respiratory distress syndrome and complicated with lung cavitations growing sp. COVID-19, to our knowledge, has rarely been associated with subacute invasive pulmonary aspergillosis with aspergillomas. Subacute invasive pulmonary aspergillosis as a superimposed infection in patients with SARS-CoV-2 is a rare entity. By reporting this case, we would like to make the readers aware of this association.

摘要

严重急性呼吸综合征冠状病毒2感染(SARS-CoV-2),通常称为COVID-19(2019冠状病毒病),始于中国湖北省武汉市。它被认为是最严重的大流行病之一,已造成人员伤亡并损害世界经济。COVID-19感染主要影响肺部,引发严重的低氧性呼吸衰竭,还为叠加的细菌和真菌感染提供了病灶。我们报告了一例73岁男性病例,该患者出现进行性呼吸困难;诊断为与SARS-CoV-2相关的严重急性呼吸窘迫综合征,并伴有肺空洞形成,培养出sp。据我们所知,COVID-19很少与伴有曲菌球的亚急性侵袭性肺曲霉病相关。亚急性侵袭性肺曲霉病作为SARS-CoV-2患者的叠加感染是一种罕见情况。通过报告此病例,我们希望让读者了解这种关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1647/7570291/2e2d2a6efd10/10.1177_2324709620966475-fig1.jpg

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