Ridel P R, Dedet J P, Esterre P
J Parasitol. 1987 Aug;73(4):769-73.
Monocyte-derived blood macrophages of untreated patients with Leishmania braziliensis or Leishmania mexicana amazonensis infections show anomalies in their nonspecific immune functions. Their ability to kill HeLa cells or to produce interleukin-1 in vitro in response to lipopolysaccharide plus Candida albicans is lower than controls indicating that acquired or innate macrophage deficiencies may be involved in the course of the disease.
未治疗的巴西利什曼原虫或亚马逊墨西哥利什曼原虫感染患者的单核细胞源性血液巨噬细胞在其非特异性免疫功能方面表现出异常。它们在体外杀死HeLa细胞或对脂多糖加白色念珠菌产生白细胞介素-1的能力低于对照组，这表明获得性或先天性巨噬细胞缺陷可能与疾病进程有关。
