浓缩人乳：一种创新的即时护理设备，旨在增加早产儿的人乳喂养选择。
Concentrating human milk: an innovative point-of-care device designed to increase human milk feeding options for preterm infants.
机构信息
Mother's Milk Is Best, Inc., Tyngsborough, MA, USA.
UCHealth, Fort Collins, CO, USA.
出版信息
J Perinatol. 2021 Mar;41(3):582-589. doi: 10.1038/s41372-020-00820-x. Epub 2020 Oct 15.
OBJECTIVE
The purpose of this study was to determine whether a point-of-care osmotic device concentrates important human milk (HM) nutrients to support feeding neonates requiring high-nutrient, low-volume feedings.
STUDY DESIGN
Raw and pasteurized HM samples were concentrated to determine the effects of time and temperature on concentration. Concentrated samples were compared with matched baseline samples to measure changes in selected nutrient concentrations. Furthermore, changes in concentration of certain bioactive components of raw milk samples were measured.
RESULT
The device significantly increased the concentrations of the majority of the measured nutrient and bioactive levels (p < 0.05). Increasing temperature of HM from 4 to 37 °C increased the concentration rate >30%. In all cases, the concentration rate of pasteurized HM was greater than that of raw HM.
CONCLUSIONS
The osmotic concentration of HM is a promising option for neonatal nutrition. Further studies are needed to establish an evidence base for the practical applications of this point-of-care device.
目的
本研究旨在确定一种即时渗透压设备是否能够浓缩重要的人乳（HM）营养成分，以支持需要高营养、低体积喂养的新生儿的喂养。
研究设计
对生乳和巴氏消毒乳样本进行浓缩，以确定时间和温度对浓缩的影响。将浓缩样本与匹配的基础样本进行比较，以测量选定营养素浓度的变化。此外，还测量了生乳样本中某些生物活性成分的浓缩变化。
结果
该设备显著增加了大多数测量营养素和生物活性成分的浓度（p<0.05）。将 HM 的温度从 4°C 升高到 37°C 会使浓缩速度提高>30%。在所有情况下，巴氏消毒 HM 的浓缩速度都大于生 HM。
结论
HM 的渗透压浓缩是新生儿营养的一个有前途的选择。需要进一步的研究来为这种即时护理设备的实际应用建立证据基础。
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