Oostendorp Rob A B, Elvers J W Hans, van Trijffel Emiel, Rutten Geert M, Scholten-Peeters Gwendolyne G M, Heijmans Marcel, Hendriks Erik, Mikolajewska Emilia, De Kooning Margot, Laekeman Marjan, Nijs Jo, Roussel Nathalie, Samwel Han
Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
Department of Manual Therapy, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.
Patient Prefer Adherence. 2020 Sep 28;14:1733-1750. doi: 10.2147/PPA.S262578. eCollection 2020.
Whiplash-associated disorders (WADs) constitute a state of health characterized by a wide diversity of symptoms as a result of impairments of functions, activity limitations, and participation restrictions. Patient-reported outcome measurements (PROMs) and patient-reported outcomes (PROs) seem appropriate when describing and evaluating the health status of patients with WAD.
To measure the use of PROMs and PROs as quality indicators in clinical reasoning, and to analyze and evaluate pre- and post-treatment 'pain intensity' and 'functioning', and for 'perceived improvement' in patients with WAD in primary care physiotherapy practice by year of referral, with the phase after accident and prognostic health profile embedded in the clinical reasoning process.
Data were collected over a period of 10 years. Pain intensity, functioning, and perceived improvement were measured using the Visual Analogue Scale for Pain (VAS-P), the Neck Disability Index (NDI) and the Global Perceived Effect scale (GPE). Pre- and post-treatment mean differences were tested for statistical significance and compared to minimal clinically important differences (MCID). Effect sizes were expressed as Cohen's d. Multivariable regression analysis was performed to explore independent associations of year of referral, phase after the accident, and the patient's prognostic health profile with post-treatment pain intensity and functioning.
A consecutive sample of 523 patients was included. Pre- and post-treatment mean differences on VAS-P and NDI were statistically significant (<0.000) and clinically relevant, with 'large' effect sizes for pain intensity and functioning. MCIDs were achieved by 80% for VAS-P and for 60% for NDI. Year of referral and phase after the accident were independently associated with worse post-treatment functioning. About half of the patients (n=241 [46.1%]) perceived themselves as improved.
The PROMs and PROs pain intensity, functioning and perceived improvement were integrated as quality indicators in the physiotherapy clinical reasoning process for patients with WAD. Significant differences in pain intensity and functioning were found but were unrelated to year of referral, phase after whiplash-related injury or prognostic health profile. The MCID VAS-P scores did not differ depending on experienced pain.
挥鞭样损伤相关疾病(WADs)是一种健康状态,其特征是由于功能受损、活动受限和参与受限而出现各种各样的症状。在描述和评估WAD患者的健康状况时,患者报告的结局测量指标(PROMs)和患者报告的结局(PROs)似乎是合适的。
在基层物理治疗实践中,通过转诊年份,测量PROMs和PROs作为临床推理质量指标的使用情况,并分析和评估WAD患者治疗前和治疗后的“疼痛强度”和“功能”,以及“感知改善”情况,同时将事故后阶段和预后健康状况纳入临床推理过程。
数据收集历时10年。使用疼痛视觉模拟量表(VAS-P)、颈部功能障碍指数(NDI)和总体感知效果量表(GPE)测量疼痛强度、功能和感知改善情况。对治疗前和治疗后的平均差异进行统计学显著性检验,并与最小临床重要差异(MCID)进行比较。效应大小用科恩d值表示。进行多变量回归分析,以探讨转诊年份、事故后阶段和患者预后健康状况与治疗后疼痛强度和功能的独立关联。
纳入了523例连续样本患者。VAS-P和NDI治疗前和治疗后的平均差异具有统计学显著性(<0.000)且具有临床相关性,疼痛强度和功能的效应大小为“大”。VAS-P的MCID达成率为80%,NDI的达成率为60%。转诊年份和事故后阶段与治疗后较差的功能独立相关。约一半的患者(n = 241 [46.1%])认为自己有所改善。
PROMs和PROs中的疼痛强度、功能和感知改善被整合为WAD患者物理治疗临床推理过程中的质量指标。发现疼痛强度和功能有显著差异,但与转诊年份、挥鞭样损伤相关损伤后的阶段或预后健康状况无关。VAS-P的MCID评分不因经历的疼痛而有所不同。