Sanders Kimberly, Thomas Ashley, Isache Carmen, Siddiqi Anwer
Department of Internal Medicine, University of Florida College of Medicine Jacksonville, Jacksonville, FL, USA.
Department of Pathology, University of Florida College of Medicine Jacksonville, Jacksonville, FL, USA.
Case Rep Gastrointest Med. 2020 Sep 30;2020:8842936. doi: 10.1155/2020/8842936. eCollection 2020.
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and can arise from any form of chronic liver disease or cirrhosis. With increasing rates of metabolic syndrome and obesity, it is not surprising that NASH is quickly becoming a leading cause of chronic liver disease and HCC in the western hemisphere (Wang and Malhi, 2018). Metastasis is usually found in advanced stages of the disease, owing to its poor prognosis. The lung, bone, and lymph nodes are the most frequent sites of metastasis (Balogh et al., 2016, and Becker et al., 2014). On the other hand, metastasis to the skin and cranium is relatively rare. Literature review reveals less than 10 reported cases in the last 10 years. Herein, we report an unusual case of a "forehead hematoma" leading to the formal diagnosis of metastatic HCC.
