Ghazanfari Behzad, Zhang Sixian, Afghah Fatemeh, Payton-McCauslin Nathan
School of Informatics, Computing and Cyber Security, Northern Arizona University, Flagstaff, AZ.
Proceedings (IEEE Int Conf Bioinformatics Biomed). 2019 Nov;2019:2350-2355. doi: 10.1109/bibm47256.2019.8983408. Epub 2020 Feb 6.
The high rate of false alarms is a key challenge related to patient care in intensive care units (ICUs) that can result in delayed responses of the medical staff. Several rule-based and machine learning-based techniques have been developed to address this problem. However, the majority of these methods rely on the availability of different physiological signals such as different electrocardiogram (ECG) leads, arterial blood pressure (ABP), and photoplethysmogram (PPG), where each signal is analyzed by an independent processing unit and the results are fed to an algorithm to determine an alarm. That calls for novel methods that can accurately detect the cardiac events by only accessing one signal (e.g., ECG) with a low level of computation and sensors requirement. We propose a novel and robust representation learning framework for ECG analysis that only rely on a single lead ECG signal and yet achieves considerably better performance compared to the state-of-the-art works in this domain, without relying on an expert knowledge. We evaluate the performance of this method using the "2015 Physionet computing in cardiology challenge" dataset. To the best of our knowledge, the best previously reported performance is based on both expert knowledge and machine learning where all available signals of ECG, ABP and PPG are utilized. Our proposed method reaches the performance of 97.3%, 95.5 %, and 90.8 % in terms of sensitivity, specificity, and the challenge's score, respectively for the detection of five arrhythmias when only one single ECG lead signals is used without any expert knowledge.
误报率高是重症监护病房(ICU)中与患者护理相关的一个关键挑战,可能导致医护人员反应延迟。已经开发了几种基于规则和基于机器学习的技术来解决这个问题。然而,这些方法大多依赖于不同生理信号的可用性,如不同的心电图(ECG)导联、动脉血压(ABP)和光电容积脉搏波描记图(PPG),每个信号由一个独立的处理单元进行分析,结果输入算法以确定警报。这就需要新的方法,能够仅通过访问一个信号(如ECG),以低计算量和低传感器要求准确检测心脏事件。我们提出了一种用于ECG分析的新颖且强大的表示学习框架,该框架仅依赖单导联ECG信号,但与该领域的现有技术相比仍实现了显著更好的性能,且不依赖专家知识。我们使用“2015年生理网心脏病学计算挑战赛”数据集评估了该方法的性能。据我们所知,之前报告的最佳性能是基于专家知识和机器学习,利用了ECG、ABP和PPG的所有可用信号。当仅使用一个单导联ECG信号且无任何专家知识时,我们提出的方法在检测五种心律失常时,灵敏度、特异性和挑战赛分数分别达到了97.3%、95.5%和90.8%。