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视力障碍、视力矫正与中老年中国人认知能力下降:来自中国健康与养老追踪调查的证据。

Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study.

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.

Medical Informatics Center, Peking University Medical Informatics Center, Beijing, China.

出版信息

Aging Ment Health. 2021 Nov;25(11):2028-2035. doi: 10.1080/13607863.2020.1828271. Epub 2020 Oct 16.

Abstract

OBJECTIVES

To investigate the associations between vision impairment (VI), vision correction (VC), and cognitive function.

METHOD

We included 20,677 participants aged ≥45 years from the China Health and Retirement Longitudinal Study (2011-2015). Participants were grouped into no VI, distance VI (DVI) only, near VI (NVI) only, or both distance and near VI (DNVI), and VI(+)/VC(-), VI(+)/VC(+), VI(-)/VC(-), or VI(-)/VC(+) further at baseline. Cognitive function at baseline and subsequently every two years was applied as a dependent variable in a generalized estimating equation model.

RESULTS

DVI only, NVI only, and DNVI had significantly worse cognitive function over time than no VI (all  < .05). DNVI had significantly worse cognitive function over time than DVI only and NVI only (all  < .001). VI(+)/VC(+), VI(-)/VC(-), and VI(-)/VC(+) had significantly better cognitive function over time than VI(+)/VC(-) (all  < .05). VI(-)/VC(+) had significantly better cognitive function over time than VI(+)/VC(+) and VI(-)/VC(-) (all  < .05).

CONCLUSION

Cognitive function was worse in middle-aged and older Chinese with VI, especially in those with DNVI. VC was associated with better cognitive function over time regardless of the status of vision.

摘要

目的

探讨视力障碍(VI)、视力矫正(VC)与认知功能之间的关联。

方法

我们纳入了来自中国健康与养老追踪调查(2011-2015 年)的 20677 名年龄≥45 岁的参与者。参与者分为无 VI、仅远视力 VI(DVI)、仅近视力 VI(NVI)或远、近视力均 VI(DNVI),以及 VI(+)/VC(-)、VI(+)/VC(+)、VI(-)/VC(-)或 VI(-)/VC(+)。在基线时,应用认知功能作为因变量,采用广义估计方程模型。

结果

仅 DVI、仅 NVI 和 DNVI 的认知功能随时间推移显著下降,均明显差于无 VI(均  < .05)。DNVI 的认知功能随时间推移显著差于仅 DVI 和仅 NVI(均  < .001)。VI(+)/VC(+)、VI(-)/VC(-)和 VI(-)/VC(+)的认知功能随时间推移显著优于 VI(+)/VC(-)(均  < .05)。VI(-)/VC(+)的认知功能随时间推移显著优于 VI(+)/VC(+)和 VI(-)/VC(-)(均  < .05)。

结论

在中国中老年人群中,VI 尤其是 DNVI 与较差的认知功能相关。无论视力状况如何,VC 与认知功能的改善相关。

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