Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Medical Informatics Center, Peking University Medical Informatics Center, Beijing, China.
Aging Ment Health. 2021 Nov;25(11):2028-2035. doi: 10.1080/13607863.2020.1828271. Epub 2020 Oct 16.
To investigate the associations between vision impairment (VI), vision correction (VC), and cognitive function.
We included 20,677 participants aged ≥45 years from the China Health and Retirement Longitudinal Study (2011-2015). Participants were grouped into no VI, distance VI (DVI) only, near VI (NVI) only, or both distance and near VI (DNVI), and VI(+)/VC(-), VI(+)/VC(+), VI(-)/VC(-), or VI(-)/VC(+) further at baseline. Cognitive function at baseline and subsequently every two years was applied as a dependent variable in a generalized estimating equation model.
DVI only, NVI only, and DNVI had significantly worse cognitive function over time than no VI (all < .05). DNVI had significantly worse cognitive function over time than DVI only and NVI only (all < .001). VI(+)/VC(+), VI(-)/VC(-), and VI(-)/VC(+) had significantly better cognitive function over time than VI(+)/VC(-) (all < .05). VI(-)/VC(+) had significantly better cognitive function over time than VI(+)/VC(+) and VI(-)/VC(-) (all < .05).
Cognitive function was worse in middle-aged and older Chinese with VI, especially in those with DNVI. VC was associated with better cognitive function over time regardless of the status of vision.
探讨视力障碍(VI)、视力矫正(VC)与认知功能之间的关联。
我们纳入了来自中国健康与养老追踪调查(2011-2015 年)的 20677 名年龄≥45 岁的参与者。参与者分为无 VI、仅远视力 VI(DVI)、仅近视力 VI(NVI)或远、近视力均 VI(DNVI),以及 VI(+)/VC(-)、VI(+)/VC(+)、VI(-)/VC(-)或 VI(-)/VC(+)。在基线时,应用认知功能作为因变量,采用广义估计方程模型。
仅 DVI、仅 NVI 和 DNVI 的认知功能随时间推移显著下降,均明显差于无 VI(均 < .05)。DNVI 的认知功能随时间推移显著差于仅 DVI 和仅 NVI(均 < .001)。VI(+)/VC(+)、VI(-)/VC(-)和 VI(-)/VC(+)的认知功能随时间推移显著优于 VI(+)/VC(-)(均 < .05)。VI(-)/VC(+)的认知功能随时间推移显著优于 VI(+)/VC(+)和 VI(-)/VC(-)(均 < .05)。
在中国中老年人群中,VI 尤其是 DNVI 与较差的认知功能相关。无论视力状况如何,VC 与认知功能的改善相关。