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瑞士基于人群队列研究中小肠炎发病率的增加。

Increasing Incidence of Microscopic Colitis in a Population-Based Cohort Study in Switzerland.

机构信息

Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

出版信息

Clin Gastroenterol Hepatol. 2021 Oct;19(10):2205-2206. doi: 10.1016/j.cgh.2020.10.015. Epub 2020 Oct 14.

Abstract

Microscopic colitis (MC) is a chronic inflammatory disease of the colon that presents with chronic, nonbloody watery diarrhea and only few or no endoscopic abnormalities. Histologic examination discriminates lymphocytic colitis (LyC; presence of ≥20 intraepithelial lymphocytes per 100 surface epithelial cells) and collagenous colitis (CC; colonic subepithelial collagen band >10 μm in diameter). MC not otherwise specified describes a subgroup of patients who do not fulfill the diagnostic criteria for either CC or LyC. Population-based epidemiologic data regarding MC are scarce. We aimed to evaluate the clinical presentation at diagnosis, incidence, and prevalence of MC in Cantons of Vaud and Fribourg, Switzerland.

摘要

显微镜下结肠炎(MC)是一种慢性结肠炎症性疾病,表现为慢性、非血性水样腹泻,仅有少数或无内镜下异常。组织学检查可区分淋巴细胞性结肠炎(LyC;每 100 个表面上皮细胞中存在≥20 个上皮内淋巴细胞)和胶原性结肠炎(CC;结肠黏膜下胶原带直径>10μm)。非特异性显微镜下结肠炎描述了一组不符合 CC 或 LyC 诊断标准的患者亚组。关于 MC 的基于人群的流行病学数据很少。我们旨在评估瑞士沃州和弗里堡州 MC 的诊断时临床表现、发病率和患病率。

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