暴露于空气污染与髋部骨折风险：韩国一项基于人群的队列研究，随访时间为 6 年。
Exposure to Air Pollution and Risk of Hip Fracture: A Population-Based Cohort Study With a 6-Year Follow-Up in South Korea.
机构信息
Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
出版信息
J Occup Environ Med. 2020 Dec;62(12):1034-1039. doi: 10.1097/JOM.0000000000002041.
OBJECTIVES
We aimed to investigate whether exposure to air pollutants was associated with the risk of hip fracture.
METHODS
We extracted data on a 2010 cohort of the adult population (more than or equal to 30 years old) from a South Korean database.
RESULTS
A total of 178,147 individuals were included in the analysis, and hip fracture had occurred in 919 individuals (0.5%). In a multivariable logistic regression model, a 1 mcg/m increase in concentrations of particulate matter measuring of less than or equal to 10 μm was associated with 2% increase in hip fracture risk (odds ratio [OR]: 1.02, 95% confidence interval [CI]: 1.01 to 1.03; P = 0.039); there were no significant associations between hip fracture risk and exposure to SO2 (P = 0.076), ozone (P = 0.220), carbon monoxide (P = 0.698), or sulfur dioxide (P = 0.114).
CONCLUSIONS
Particular matter air concentration may be a modifiable risk factor for hip fracture.
目的
我们旨在探究暴露于空气污染物是否与髋部骨折风险相关。
方法
我们从韩国数据库中提取了 2010 年队列的成人（年龄大于或等于 30 岁）数据。
结果
共纳入 178147 人，919 人发生髋部骨折（0.5%）。在多变量逻辑回归模型中，浓度为 10μm 的颗粒物每增加 1mcg/m，髋部骨折风险增加 2%（比值比[OR]：1.02，95%置信区间[CI]：1.01 至 1.03；P=0.039）；暴露于 SO2（P=0.076）、臭氧（P=0.220）、一氧化碳（P=0.698）或二氧化硫（P=0.114）与髋部骨折风险之间无显著关联。
结论
特定物质空气浓度可能是髋部骨折的可改变风险因素。
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