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交叉与横向克氏针固定治疗儿童肱骨髁上骨折:随机对照试验的荟萃分析。

Crossed versus lateral K-wire fixation of supracondylar fractures of the humerus in children: a meta-analysis of randomized controlled trials.

机构信息

Department of Orthopedics and Traumatology, Federal University of São Paulo, São Paulo, Brazil.

Department of Orthopedics and Traumatology, Federal University of São Paulo, São Paulo, Brazil.

出版信息

J Shoulder Elbow Surg. 2021 Feb;30(2):439-448. doi: 10.1016/j.jse.2020.09.021. Epub 2020 Oct 16.

Abstract

BACKGROUND

Supracondylar fractures of the humerus are common in children. Whether fixation should be performed with crossed or lateral wires remains controversial. We performed a meta-analysis of randomized controlled trials to evaluate both techniques in terms of the function of the elbow and the risk of neurologic injury and loss of reduction. We also assessed the quality of the evidence currently available.

METHODS

The MEDLINE, Embase, Cochrane Library, and LILACS (Latin American and Caribbean Health Sciences Literature) databases, as well as ongoing clinical trial databases, were searched until March 2020. The main outcomes were function, measured by the Flynn criteria, and complications (neurologic lesions and loss of reduction). A meta-analysis was conducted using relative risk (RR) analysis for dichotomous variables and difference in means for continuous variables. Heterogeneity was tested using the I statistic.

RESULTS

Twelve trials, with a total of 930 patients, met the inclusion criteria. Both groups (crossed-wire and lateral-wire fixation) presented satisfactory functional results, with no difference between them (RR, 0.99; 95% confidence interval [CI], 0.96-1.02; P = .44). Patients undergoing crossed-wire fixation had a higher risk of iatrogenic neurologic injury (RR, 0.45; 95% CI, 0.21-0.99; P = .05). The crossed group showed greater fixation stability, with a lower incidence of loss of fracture reduction (RR, 1.39; 95% CI, 1.04-1.85; P = .03). The GRADEpro GDT (Guideline Development Tool) showed that the quality of evidence of the evaluated outcomes was low or very low.

CONCLUSION

There is evidence of very low quality that fixation with lateral wires is safer regarding iatrogenic nerve lesions whereas fixation with crossed wires is more effective at maintaining fracture reduction.

摘要

背景

肱骨髁上骨折在儿童中较为常见。交叉或外侧钢针固定哪种方法更好,目前仍存在争议。我们对随机对照试验进行了荟萃分析,旨在评估这两种技术在肘部功能、神经损伤风险和复位丢失方面的效果。我们还评估了目前可用证据的质量。

方法

我们检索了 MEDLINE、Embase、Cochrane 图书馆和 LILACS(拉丁美洲和加勒比健康科学文献)数据库,以及正在进行的临床试验数据库,检索时间截至 2020 年 3 月。主要结局是功能,采用 Flynn 标准进行评估;次要结局是并发症(神经损伤和复位丢失)。使用相对危险度(RR)分析二分类变量,使用均数差值分析连续变量。使用 I ²检验评估异质性。

结果

12 项试验,共纳入 930 例患者,符合纳入标准。两组(交叉钢针固定组和外侧钢针固定组)的功能结果均令人满意,两组之间无差异(RR,0.99;95%置信区间[CI],0.96-1.02;P =.44)。交叉钢针固定组医源性神经损伤风险更高(RR,0.45;95% CI,0.21-0.99;P =.05)。交叉钢针组固定稳定性更好,骨折复位丢失发生率更低(RR,1.39;95% CI,1.04-1.85;P =.03)。GRADEpro GDT(指南制定工具)显示,评估结局的证据质量为低或极低。

结论

有低质量证据表明,外侧钢针固定在预防医源性神经损伤方面更安全,而交叉钢针固定在维持骨折复位方面更有效。

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