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认知功能:层级结构还是全协同制?

Cognitive function: holarchy or holacracy?

机构信息

Department of Neurosciences, "Iuliu Hatieganu" University of Medicine and Pharmacy, No. 37 Mircea Eliade Street, 400486, Cluj-Napoca, Romania.

"RoNeuro" Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.

出版信息

Neurol Sci. 2021 Jan;42(1):89-99. doi: 10.1007/s10072-020-04737-3. Epub 2020 Oct 18.

Abstract

Cognition is the most complex function of the brain. When exploring the inner workings of cognitive processes, it is crucial to understand the complexity of the brain's dynamics. This paper aims to describe the integrated framework of the cognitive function, seen as the result of organization and interactions between several systems and subsystems. We briefly describe several organizational concepts, spanning from the reductionist hierarchical approach, up to the more dynamic theory of open complex systems. The homeostatic regulation of the mechanisms responsible for cognitive processes is showcased as a dynamic interplay between several anticorrelated mechanisms, which can be found at every level of the brain's organization, from molecular and cellular level to large-scale networks (e.g., excitation-inhibition, long-term plasticity-long-term depression, synchronization-desynchronization, segregation-integration, order-chaos). We support the hypothesis that cognitive function is the consequence of multiple network interactions, integrating intricate relationships between several systems, in addition to neural circuits.

摘要

认知是大脑最复杂的功能。在探索认知过程的内在运作机制时,理解大脑动态的复杂性至关重要。本文旨在描述认知功能的综合框架,将其视为几个系统和子系统之间组织和相互作用的结果。我们简要描述了几个组织概念,从还原论层次方法到更动态的开放复杂系统理论。负责认知过程的机制的动态调节被展示为几个负相关机制之间的动态相互作用,可以在大脑组织的各个层次上找到,从分子和细胞水平到大规模网络(例如,兴奋-抑制、长时程可塑性-长时程抑制、同步-去同步、分离-整合、有序-混沌)。我们支持这样一种假设,即认知功能是多个网络相互作用的结果,整合了几个系统之间复杂的关系,以及神经回路。

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