Student Research committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran 1983969411, Iran.
Student Research Committee, Babol University of Medical Sciences, Babol 4717647745, Iran.
Rev Cardiovasc Med. 2020 Sep 30;21(3):385-397. doi: 10.31083/j.rcm.2020.03.78.
After the emergence of the novel 2019 coronavirus disease in P. R. China, this highly contagious disease has been currently spread out to almost all countries, worldwide. Novel 2019 coronavirus disease, Middle East respiratory syndrome, and severe acute respiratory syndrome are reported to cause a higher risk for severe infections in patients with chronic comorbidities, such as hypertension and diabetes. These severe infections can contribute to higher rates of morbidity and mortality in these patients. In the present review, we discussed the role and underlying mechanisms of the two most common chronic diseases, type-2 diabetes mellitus and hypertension, in clinical manifestations and disease severity of novel 2019 coronavirus disease, Middle East respiratory syndrome and severe acute respiratory syndrome, with the hope to provide evidence for better decision-making in the treatment of this vulnerable population.
在中国出现新型 2019 冠状病毒病后，这种高度传染性疾病目前已在全球几乎所有国家传播。据报道，新型 2019 冠状病毒病、中东呼吸综合征和严重急性呼吸综合征使患有高血压和糖尿病等慢性合并症的患者发生严重感染的风险更高。这些严重感染可能导致这些患者的发病率和死亡率更高。在本综述中，我们讨论了两种最常见的慢性疾病，即 2 型糖尿病和高血压，在新型 2019 冠状病毒病、中东呼吸综合征和严重急性呼吸综合征的临床表现和疾病严重程度中的作用及其潜在机制，希望为这一脆弱人群的治疗提供更好决策的证据。
