Yang Huisi, Bao Jing, Qi Yanli, Zhao JiaYing, Hu Yian, Wu Weixuan, Wu Xicheng, Zhong Daidi, Huo Danqun, Hou Changjun
Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, PR China.
Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, PR China.
Anal Chim Acta. 2020 Oct 23;1135:12-19. doi: 10.1016/j.aca.2020.08.010. Epub 2020 Aug 21.
Herein, a three-dimensional graphene wall (GWs) and nano-CuO modified carbon fiber paper (CFP) electrode were used to develop a disposable and sensitive non-enzymatic glucose sensor. This sensing interface of GWs/CuO consists of an interlaced CFP on which intercrossed graphene walls (GWs) were vertically tethered in situ by radio frequency plasma enhanced chemical vapor deposition (RF-PECVD), and CuO nanoparticles (NPs) were evenly grew on the 3D GWs layer and skeleton through the complete thermal decomposition of copper acetate (Cu (CHCOO)) at high temperature. The CFP/GWs/CuO shows a large specific surface area and rich solution diffusion channels, which can expose more catalytic active sites without Nafion fixation film, thus greatly improving the electrocatalytic performance of this glucose sensor. The CFP/GWs/CuO sensor shows excellent catalytic performance to glucose with a linear detection range of 0.5 μM-5166 μM, LOD of 0.21 μM, and response time <4 s. This kind of disposable and sensitive electrode can capable of controlling uniform growth and accurate quantification, and has great development potential in the field of medical detection and the commercialization of wearable sensors.
在此，使用三维石墨烯壁（GWs）和纳米CuO修饰的碳纤维纸（CFP）电极开发了一种一次性且灵敏的非酶葡萄糖传感器。GWs/CuO这种传感界面由交织的CFP组成，通过射频等离子体增强化学气相沉积（RF-PECVD）将交叉的石墨烯壁（GWs）原位垂直连接在CFP上，并且CuO纳米颗粒（NPs）通过乙酸铜（Cu(CHCOO)）在高温下的完全热分解在三维GWs层和骨架上均匀生长。CFP/GWs/CuO具有大的比表面积和丰富的溶液扩散通道，在没有Nafion固定膜的情况下可以暴露更多的催化活性位点，从而极大地提高了这种葡萄糖传感器的电催化性能。CFP/GWs/CuO传感器对葡萄糖表现出优异的催化性能，线性检测范围为0.5 μM - 5166 μM，检测限为0.21 μM且响应时间<4 s。这种一次性且灵敏的电极能够控制均匀生长和精确量化，在医学检测领域和可穿戴传感器商业化方面具有巨大的发展潜力。
