College of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan, 250200, PR China.
School of Materials Science and Engineering, Key Laboratory of Display Materials and Photoelectric Devices, Ministry of Education and Tianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology, Tianjin, 300384, PR China.
Mikrochim Acta. 2024 Jul 6;191(8):451. doi: 10.1007/s00604-024-06510-1.
TiCT MXene/CuO composites were prepared by acid etching combined with electrochemical technique. The abundant active sites on the surface of MXene greatly increase the loading of CuO nanoparticles, and the synergistic effect between the different components of the composite can accelerate the oxidation reaction of glucose. The results indicate that at the working potential of 0.55 V (vs. Ag/AgCl), the glucose sensor based on TiCT MXene/CuO composite presents large linear concentration ranges from 1 µM to 4.655 mM (sensitivity of 361 µA mM cm) and from 5.155 mM to 16.155 mM (sensitivity of 133 µA mM cm). The limit of detection is 0.065 µM. In addition, the sensor effectively avoids the oxidative interference of common interfering species such as ascorbic acid, dopamine and uric acid. The sensor has good reproducibility, stability and acceptable recoveries for the detection of glucose in human sweat sample (97.5-103.3%) with RSD values less than 4%. Based on these excellent properties it has great potential for the detection of glucose in real samples.
TiCT MXene/CuO 复合材料通过酸刻蚀结合电化学技术制备。MXene 表面丰富的活性位点极大地增加了 CuO 纳米粒子的负载量，复合材料中不同组分的协同作用可以加速葡萄糖的氧化反应。结果表明，在工作电位为 0.55 V（相对于 Ag/AgCl）时，基于 TiCT MXene/CuO 复合材料的葡萄糖传感器呈现出从 1 μM 到 4.655 mM（灵敏度为 361 μA mM cm）和从 5.155 mM 到 16.155 mM（灵敏度为 133 μA mM cm）的大线性浓度范围。检测限为 0.065 μM。此外，该传感器有效地避免了抗坏血酸、多巴胺和尿酸等常见干扰物质的氧化干扰。该传感器具有良好的重现性、稳定性和对人汗液样本中葡萄糖的检测的可接受回收率（97.5-103.3%），RSD 值小于 4%。基于这些优异的性能，它在实际样品中检测葡萄糖具有很大的潜力。
