Institute of Pathology, University Hospital of Modena, Modena, Italy.
Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia, Modena, Italy; Second Opinion Medical Network, Modena, Italy.
Vaccine. 2020 Nov 10;38(48):7581-7584. doi: 10.1016/j.vaccine.2020.10.013. Epub 2020 Oct 9.
Today, Coronavirus Disease 2019 (COVID-19) is a global public health emergency and vaccination measures to counter its diffusion are deemed necessary. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of the disease, unleashes a T-helper 2 immune response in those patients requiring intensive care. Here, we illustrate the immunological mechanism to train the immune system towards a more effective and less symptomatic T-helper 1 immune response, to be exploited against SARS-CoV-2.
今天，2019 年冠状病毒病（COVID-19）是一场全球性的公共卫生紧急事件，有必要采取疫苗接种措施来对抗其传播。引发该疾病的严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）会在需要重症监护的患者中引发 T 辅助 2 免疫反应。在这里，我们阐述了免疫机制，旨在训练免疫系统产生更有效和症状较轻的 T 辅助 1 免疫反应，以对抗 SARS-CoV-2。
