Department of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, India.
Department of General Medicine, All India Institute of Medical Sciences, Rishikesh, India.
Cancer Rep (Hoboken). 2021 Feb;4(1):e1307. doi: 10.1002/cnr2.1307. Epub 2020 Oct 19.
Tripe palms (TP) is one of the rare cutaneous paraneoplastic manifestations of various intra-abdominal malignancies. TP and malignant acanthosis nigricans (MAN) occur together and may precede even years before the index cancer. Though rare, the clinical significance of TP and MAN holds significance as an indicator of internal malignancy.
Here, we describe 71-year, postmenopausal female with ovarian cancer who presented to us with a history of dyspepsia, abdominal distension, and weight loss. On detailed history and evaluation, it was found that she had TP and MAN 4 years before diagnosis.
The unique presentation preceding the primary illness necessitates extensive early work-up to look for malignancy and the initial consideration for surgery due to the tumor biology in such patients.
三掌棕榈（TP）是各种腹腔内恶性肿瘤罕见的皮肤副肿瘤表现之一。TP 和恶性黑棘皮病（MAN）同时发生，甚至可能在指数癌症之前提前数年发生。尽管罕见，但 TP 和 MAN 的临床意义作为内部恶性肿瘤的指标具有重要意义。
在这里，我们描述了一位 71 岁绝经后女性，患有卵巢癌，她因消化不良、腹胀和体重减轻而就诊。详细的病史和评估发现，她在诊断前 4 年就已经患有 TP 和 MAN。
这种疾病在原发疾病之前就有独特的表现，这需要进行广泛的早期检查以寻找恶性肿瘤，并考虑对这些患者进行手术，因为他们的肿瘤生物学特性如此。
