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在 SARS-CoV-2(COVID-19)紧急情况下预防耳毒性。

Ototoxicity prevention during the SARS-CoV-2 (COVID-19) emergency.

机构信息

ENT & Audiology Department, University Hospital of Ferrara, Cona, Italy.

Institute of Physiology and Pathology of Hearing, Warsaw, Poland; Department of Heart Failure and Cardiac Rehabilitation, Medical University of Warsaw, Warsaw, Poland; Institute of Sensory Organs, Kajetany, Poland.

出版信息

J Glob Antimicrob Resist. 2020 Dec;23:263-264. doi: 10.1016/j.jgar.2020.09.030. Epub 2020 Oct 17.

Abstract

Aim of this paper is to remind the risk of ototoxicity when using chloroquine and hydroxychloroquine, in particular as prophylactic agents against SARS-CoV-2, during the pandemic. Healthy subjects taking chloroquine and hydroxychloroquine as prophylactic agents against SARS-CoV-2, during the pandemic, should be screened periodically, at least by Otoacoustic Emissions (OAEs) in order to detect early manifestations of possible cochlear ototoxic damages.

摘要

本文旨在提醒在大流行期间使用氯喹和羟氯喹(尤其是作为预防 SARS-CoV-2 的药物)时存在耳毒性风险。在大流行期间,服用氯喹和羟氯喹作为预防 SARS-CoV-2 的药物的健康受试者应定期进行筛查,至少通过耳声发射(OAE)进行筛查,以便早期发现可能的耳蜗耳毒性损害的表现。

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本文引用的文献

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Chloroquine as a prophylactic agent against COVID-19?氯喹作为 COVID-19 的预防药物?
Int J Antimicrob Agents. 2020 Jun;55(6):105980. doi: 10.1016/j.ijantimicag.2020.105980. Epub 2020 Apr 12.
3
5
Chloroquine ototoxicity.氯喹耳毒性。
Clin Rheumatol. 2007 Nov;26(11):1809-10. doi: 10.1007/s10067-007-0662-6. Epub 2007 Jun 27.
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Hydroxychloroquine ototoxicity in a patient with rheumatoid arthritis.
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