ENT & Audiology Department, University Hospital of Ferrara, Cona, Italy.
Institute of Physiology and Pathology of Hearing, Warsaw, Poland; Department of Heart Failure and Cardiac Rehabilitation, Medical University of Warsaw, Warsaw, Poland; Institute of Sensory Organs, Kajetany, Poland.
J Glob Antimicrob Resist. 2020 Dec;23:263-264. doi: 10.1016/j.jgar.2020.09.030. Epub 2020 Oct 17.
Aim of this paper is to remind the risk of ototoxicity when using chloroquine and hydroxychloroquine, in particular as prophylactic agents against SARS-CoV-2, during the pandemic. Healthy subjects taking chloroquine and hydroxychloroquine as prophylactic agents against SARS-CoV-2, during the pandemic, should be screened periodically, at least by Otoacoustic Emissions (OAEs) in order to detect early manifestations of possible cochlear ototoxic damages.
本文旨在提醒在大流行期间使用氯喹和羟氯喹（尤其是作为预防 SARS-CoV-2 的药物）时存在耳毒性风险。在大流行期间，服用氯喹和羟氯喹作为预防 SARS-CoV-2 的药物的健康受试者应定期进行筛查，至少通过耳声发射（OAE）进行筛查，以便早期发现可能的耳蜗耳毒性损害的表现。
