Beukes Eldre, Ulep Alyssa Jade, Eubank Taylor, Manchaiah Vinaya
Department of Speech and Hearing Sciences, Lamar University, Beaumont, TX 77710, USA.
Vision and Hearing Sciences Research Centre, Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1TP, UK.
J Clin Med. 2021 Jun 23;10(13):2763. doi: 10.3390/jcm10132763.
This review aimed to systematically review what has been published regarding tinnitus during the coronavirus disease 2019 (COVID-19) pandemic up to March 2021 by performing both narrative and quantitative meta-analyses. Of the 181 records identified, 33 met the inclusion criteria, which generally had a fair risk of overall bias. In the included, 28 studies focused on the impact of the COVID-19 virus on tinnitus and 5 studies focused on the impact of the pandemic on tinnitus. From the studies identifying the impact of COVID-19 on tinnitus, there were 17 cross-sectional studies ( = 8913) and 11 case series or case report studies ( = 35). There were 2 cross-sectional studies ( = 3232) and 3 pre-post-test design studies ( = 326) focusing on the impact of the pandemic on tinnitus. No consistent patterns were found regarding the presentation of the tinnitus or additional factors that could have tinnitus developing in the disease impact studies. For the pandemic impact studies, the associated stress and anxiety of the pandemic were consistently suggested to contribute to tinnitus experiences. The pooled estimated prevalence of tinnitus post COVID-19 was 8% (CI: 5 to 13%). Medical professionals should be aware that tinnitus might be more problematic following the pandemic or after having COVID-19.
本综述旨在通过叙述性分析和定量荟萃分析，系统回顾截至2021年3月在2019冠状病毒病（COVID-19）大流行期间发表的有关耳鸣的文献。在检索到的181篇记录中，33篇符合纳入标准，总体偏倚风险一般为中等。纳入的研究中，28项研究聚焦于COVID-19病毒对耳鸣的影响，5项研究聚焦于大流行对耳鸣的影响。在确定COVID-19对耳鸣影响的研究中，有17项横断面研究（n = 8913）和11项病例系列或病例报告研究（n = 35）。有2项横断面研究（n = 3232）和3项前后测试设计研究（n = 326）聚焦于大流行对耳鸣的影响。在疾病影响研究中，未发现耳鸣表现或可能导致耳鸣的其他因素存在一致模式。对于大流行影响研究，一致认为大流行相关的压力和焦虑会导致耳鸣症状。COVID-19后耳鸣的合并估计患病率为8%（CI：5%至13%）。医学专业人员应意识到，大流行后或感染COVID-19后耳鸣可能更成问题。
