Environmental Science and Technology Research Center, Department of Environmental Health Engineering, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Neurology Department, Shahid Sadoughi Hospital, Yazd University of Medical Science, Yazd, Iran.
Environ Sci Pollut Res Int. 2021 Feb;28(7):8907-8914. doi: 10.1007/s11356-020-10580-y. Epub 2020 Oct 19.
Long-term inhalation of radon gas can cause harm to humans and lead to many diseases. One of these diseases is multiple sclerosis (MS), the most common chronic disease of the central nervous system, which alters the brain structure and impedes the rapid transmission of nerve signals throughout the neuron system. Therefore, this study aimed to investigate the relationship of the radon gas concentration in residential homes of MS and non-MS individuals with their results of paraclinical MRI and VEP in Yazd City, Iran. The radon gas concentration was measured in residential homes of 44 people with MS and 100 healthy people. To this end, the questionnaire of radon gas monitoring in residential buildings was administered, and the radon gas concentration was measured by CR-39 detectors. The mean radon concentrations in the homes of MS and non-MS people were 69.51 and 70.83, respectively. A significant positive relationship was found between radon concentration and building's age (P = 0.038). Furthermore, radon concentration had a significant inverse relationship with the building's ventilation (P = 0.053) and cooling systems (P = 0.021). No significant relationship was observed between total radon concentration and MS incidence (P = 0.88). Moreover, no significant correlation was found between radon concentration and location of the plaque in MRI test results of the patients. However, it showed an inverse non-significant correlation with the plaque's number (r = - 0.12, P = 0.42). Further studies in this area are recommended.
长期吸入氡气会对人体造成伤害，并导致多种疾病。其中一种疾病是多发性硬化症（MS），这是中枢神经系统最常见的慢性疾病，它会改变大脑结构，并阻碍神经元系统中神经信号的快速传递。因此，本研究旨在探讨伊朗亚兹德市 MS 患者和非 MS 患者住宅内的氡气浓度与其临床前 MRI 和 VEP 结果之间的关系。在 44 名 MS 患者和 100 名健康人的住宅中测量了氡气浓度。为此，我们发放了住宅氡气监测问卷，并使用 CR-39 探测器测量了氡气浓度。MS 患者和非 MS 患者家中的平均氡浓度分别为 69.51 和 70.83。结果发现，氡浓度与建筑物的年龄呈显著正相关（P = 0.038）。此外，氡浓度与建筑物的通风（P = 0.053）和冷却系统（P = 0.021）呈显著负相关。总氡浓度与 MS 发病率之间未观察到显著相关性（P = 0.88）。此外，氡浓度与患者 MRI 检查结果中斑块的位置之间未发现显著相关性。然而，它与斑块数量呈负相关（r = -0.12，P = 0.42），但无统计学意义。建议在这一领域开展进一步的研究。
