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单侧冠状缝早闭严重程度的量化。

Quantification of Severity of Unilateral Coronal Synostosis.

机构信息

Department of Plastic and Reconstructive Surgery, 8124University Medical Center Utrecht, The Netherlands.

Department of Radiology, 6993Erasmus MC, Rotterdam, University Medical Center Rotterdam, The Netherlands.

出版信息

Cleft Palate Craniofac J. 2021 Jul;58(7):832-837. doi: 10.1177/1055665620965099. Epub 2020 Oct 20.

DOI:10.1177/1055665620965099
PMID:33078622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8209757/
Abstract

OBJECTIVES

Severity of unilateral coronal synostosis (UCS) can vary. Quantification is important for treatment, expectations of treatment and natural outcome, and education of the patient and parents.

DESIGN

Retrospective study.

SETTING

Primary craniofacial center.

PATIENTS, PARTICIPANTS: Twenty-three preoperative patients with unilateral coronal craniosynostosis (age < 2 years).

INTERVENTION

Utrecht Cranial Shape Quantifier (UCSQ) was used to quantify severity using the variables: asymmetry ratio of frontal peak and ratio of frontal peak gradient.

MAIN OUTCOME MEASURES(S): The UCSQ variables were combined and related to visual score using Pearson correlation coefficient; UCSQ and visual score were additionally compared to Di Rocco classification by one-way analysis of variance or Kruskal-Wallis test. All measurements were made on computed tomography scans.

RESULTS

Good correlation between UCSQ and visual score was found ( = 0.67). No statistically significant differences were found between group means of UCSQ in the 3 categories of Di Rocco classification ( = 0.047; > .05). Kruskal-Wallis test showed no significant differences between group means of visual score in the 3 categories of Di Rocco classification (Kruskal-Wallis (2) = 0.871; > .05).

CONCLUSIONS

Using UCSQ, we can quantify UCS according to severity using characteristics, it outperforms traditional methods and captures the whole skull shape. In future research, we can apply UCSQ to 3D-photogrammetry due to the utilization of external landmarks.

摘要

目的

单侧冠状缝早闭(UCS)的严重程度可能存在差异。量化严重程度对于治疗、治疗预期和自然预后以及患者和家长的教育都很重要。

设计

回顾性研究。

地点

初级颅面中心。

患者/参与者:23 例单侧冠状缝颅缝早闭的术前患者(年龄<2 岁)。

干预措施

使用 Utrecht Cranial Shape Quantifier(UCSQ),通过不对称性比和额峰梯度比来量化严重程度。

主要观察指标

UCSQ 变量采用 Pearson 相关系数与视觉评分相结合;UCSQ 和视觉评分通过单向方差分析或 Kruskal-Wallis 检验与 Di Rocco 分类进一步比较。所有测量均在计算机断层扫描上进行。

结果

发现 UCSQ 与视觉评分之间存在良好的相关性( = 0.67)。在 Di Rocco 分类的 3 个类别中,UCSQ 的组均值之间没有统计学上的显著差异( = 0.047;>0.05)。Kruskal-Wallis 检验显示,在 Di Rocco 分类的 3 个类别中,视觉评分的组均值之间没有显著差异(Kruskal-Wallis 检验(2)= 0.871;>0.05)。

结论

使用 UCSQ,我们可以根据特征对 UCS 进行严重程度的量化,优于传统方法,并且可以捕捉整个颅骨的形状。在未来的研究中,我们可以将 UCSQ 应用于 3D 摄影测量法,因为它利用了外部标志点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/0d79991cd69a/10.1177_1055665620965099-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/6d2b0b9a32a8/10.1177_1055665620965099-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/aaa671890d53/10.1177_1055665620965099-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/0d79991cd69a/10.1177_1055665620965099-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/6d2b0b9a32a8/10.1177_1055665620965099-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/aaa671890d53/10.1177_1055665620965099-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf81/8209757/0d79991cd69a/10.1177_1055665620965099-fig3.jpg

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本文引用的文献

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Eur J Pediatr. 2020 Oct;179(10):1569-1577. doi: 10.1007/s00431-020-03643-2. Epub 2020 Apr 17.
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Plagiocephaly Severity Scale to Aid in Clinical Treatment Recommendations.用于辅助临床治疗建议的斜头畸形严重程度量表。
J Craniofac Surg. 2017 May;28(3):717-722. doi: 10.1097/SCS.0000000000003520.
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Anterior plagiocephaly: epidemiology, clinical findings,diagnosis, and classification. A review.
前斜头畸形:流行病学、临床发现、诊断及分类。综述
Childs Nerv Syst. 2012 Sep;28(9):1413-22. doi: 10.1007/s00381-012-1845-2. Epub 2012 Aug 8.
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An epidemiological study of nonsyndromal craniosynostoses.非综合征性颅缝早闭的流行病学研究。
J Craniofac Surg. 2011 Jan;22(1):47-9. doi: 10.1097/SCS.0b013e3181f6c2fb.
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Evolution in the frequency of nonsyndromic craniosynostosis.非综合征性颅缝早闭症发病率的演变
J Neurosurg Pediatr. 2009 Jul;4(1):21-5. doi: 10.3171/2009.3.PEDS08355.
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The changing epidemiologic spectrum of single-suture synostoses.单缝颅缝早闭的流行病学谱变化。
Plast Reconstr Surg. 2008 Aug;122(2):527-533. doi: 10.1097/PRS.0b013e31817d548c.
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MOC-PS(SM) CME article: management considerations in the treatment of craniosynostosis.MOC-PS(SM) 继续医学教育文章:颅缝早闭治疗中的管理考量
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Active counterpositioning or orthotic device to treat positional plagiocephaly?使用主动对抗定位法还是矫形器械来治疗体位性斜头畸形?
J Craniofac Surg. 2001 Jul;12(4):308-13. doi: 10.1097/00001665-200107000-00003.
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Synostotic frontal plagiocephaly: anthropometric comparison of three techniques for surgical correction.融合性额部斜头畸形:三种手术矫正技术的人体测量学比较
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