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塞浦路斯儿童和青少年猪肉中兽用抗生素的膳食暴露评估。

Dietary Exposure Assessment of Veterinary Antibiotics in Pork Meat on Children and Adolescents in Cyprus.

作者信息

Kyriakides Demetra, Lazaris Andreas C, Arsenoglou Konstantinos, Emmanouil Maria, Kyriakides Olympia, Kavantzas Nikolaos, Panderi Irene

机构信息

Laboratory of Pathological Anatomy, Department of Clinical and Laboratory Medicine, School of Medicine, National and Kapodistrian University of Athens, 75, Mikras Asias Avenue, Goudi, 11527 Athens, Greece.

Veterinary Services, Ministry of Agriculture, Rural Development and Environment, 1417 Nicosia, Cyprus.

出版信息

Foods. 2020 Oct 16;9(10):1479. doi: 10.3390/foods9101479.

Abstract

In recent years, huge amounts of antibiotics have been administered to farm animals, and as a result, residues of these antibiotics can accumulate in livestock products and, once consumed, may be transmitted to humans. Farm animals' antibiotic treatment may therefore present a risk for consumers health, especially for children and adolescents. In children, the immune system is not fully developed, and thus, they are more susceptible than adults to resistant bacteria. A dietary exposure assessment was conducted on veterinary antibiotics found in raw pork meat among children and adolescents in Cyprus, since pork is the most consumed red meat in Cypriot population. The study was based on the results of the occurrence of 45 residual antibiotics in raw pork meat samples in Cyprus between 2012 and 2017 in combination with data on the consumption of pork meat on children and adolescents taken from the latest demographic report in Cyprus. Estimated daily intake (EDI) values of veterinary antibiotics for children aged 6-9 years old, were higher compared to EDI values for adolescents aged 10-17 years old. The percentage ratio of the estimated daily intake to the acceptable daily intake for all the veterinary antibiotic residues was less than 5.6. The results indicate that antibiotic residues in pork meat of inland production are below the acceptable daily intake and are of low risk to human health related to the exposure of antibiotics. Nevertheless, continuous exposure to low levels of antibiotic residues in respect to age vulnerability should be of a great concern.

摘要

近年来,大量抗生素被用于养殖动物,因此,这些抗生素的残留会在畜产品中蓄积,一旦被食用,可能会传播给人类。养殖动物的抗生素治疗因此可能对消费者健康构成风险,尤其是对儿童和青少年。儿童的免疫系统尚未完全发育,因此,他们比成年人更容易受到耐药菌的影响。由于猪肉是塞浦路斯民众消费最多的红肉,因此对塞浦路斯儿童和青少年生猪肉中发现的兽用抗生素进行了膳食暴露评估。该研究基于2012年至2017年塞浦路斯生猪肉样本中45种残留抗生素的出现结果,以及从塞浦路斯最新人口报告中获取的儿童和青少年猪肉消费数据。6至9岁儿童兽用抗生素的估计每日摄入量(EDI)值高于10至17岁青少年的EDI值。所有兽用抗生素残留的估计每日摄入量与可接受每日摄入量的百分比比率小于5.6。结果表明,内陆生产的猪肉中的抗生素残留低于可接受的每日摄入量,与抗生素暴露相关的对人类健康的风险较低。然而,考虑到年龄易感性,持续接触低水平的抗生素残留应引起高度关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f3d/7602826/0faad3c62deb/foods-09-01479-g001.jpg

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