DeGirolami P C, Eliopoulos G
Department of Pathology, Harvard Medical School, Boston, Massachusetts.
Clin Lab Med. 1987 Sep;7(3):499-512.
Principles and techniques of routine and special in vitro antimicrobial susceptibility testing of bacteria are reviewed with emphasis on the advantages, limitations, and potential problems of each method. The utilities of MBC testing and of serum bactericidal titer determination are discussed in the clinical context. The use of testing for possible antibiotic interactions is examined in light of potential benefits and risks of combination antimicrobial therapy.
本文综述了细菌常规及特殊体外抗菌药敏试验的原理和技术，重点阐述了每种方法的优点、局限性及潜在问题。在临床背景下讨论了最低杀菌浓度（MBC）检测和血清杀菌效价测定的应用。根据联合抗菌治疗的潜在益处和风险，探讨了检测可能存在的抗生素相互作用的用途。
