Cao Zhongru, Li Yuting, Wang Li, Liu Yanhua, Zhang Lei, Ma Li, An Yunfei, Wang Yibo, Li Huiyan
Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin 150040, P.R. China.
Ward IV, Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin 150040, P.R. China.
Iran J Public Health. 2020 Jul;49(7):1232-1241. doi: 10.18502/ijph.v49i7.3576.
To investigate the effect of perceptual stress reduction control intervention on the level of symptomatic groups at different time points in breast cancer.
A total of 124 breast cancer patients were divided into intervention group and control group, 62 cases in each group. Perioperative nursing and chemotherapy nursing were given to the control group, and the intervention group was given the interventional stress reduction control intervention. The level of symptom clusters of different time points were compared between the two groups.
The incidence and severity of myelosuppression in the intervention group were slightly lower than those in the control group. The adverse reactions of bone marrow suppression at T3 were much lower than those in the control group, and the differences were significant (=0.003, =0.043). The control group had higher incidence and more severe symptoms of nausea, vomiting and diarrhea than the intervention group (=0.002, =0.042). The symptoms of breast pain and swelling at T1 in the intervention group were significantly lower than those in the control group (=0.000, =0.000). There was no significant difference in breast symptoms between the two groups at T2 and T3 (>0.05). At the time of T2 and T3 of chemotherapy, the health promotion behavior scores of the intervention group were higher than the control group, and the difference was statistically significant (P=0.000, P=0.000).
Perceptual stress reduction control intervention can effectively relieve bone marrow suppression, digestive tract discomfort and breast symptoms, and promote health promotion behavior.
探讨感知应激减轻控制干预对乳腺癌不同时间点症状群水平的影响。
将124例乳腺癌患者分为干预组和对照组，每组62例。对照组给予围手术期护理和化疗护理，干预组给予感知应激减轻控制干预。比较两组不同时间点症状群水平。
干预组骨髓抑制的发生率和严重程度略低于对照组。T3时骨髓抑制的不良反应远低于对照组，差异有统计学意义（=0.003，=0.043）。对照组恶心、呕吐和腹泻的发生率高于干预组，症状更严重（=0.002，=0.042）。干预组T1时乳房疼痛和肿胀症状明显低于对照组（=0.000，=0.000）。两组在T2和T3时乳房症状无显著差异（>0.05）。化疗T2和T3时，干预组的健康促进行为得分高于对照组，差异有统计学意义（P=0.000，P=0.000）。
感知应激减轻控制干预可有效缓解骨髓抑制、消化道不适和乳房症状，促进健康促进行为。
