College of Physical Education, South-Central Minzu University, Wuhan, Hubei, China.
Key Laboratory of Sports and Physical Fitness Health of Ministry of Education, Beijing Sport University, Beijing, China.
Front Public Health. 2024 Sep 19;12:1451101. doi: 10.3389/fpubh.2024.1451101. eCollection 2024.
Aimed to assess the impact of wearable device-based aerobic exercise on the physical and mental well-being of women with breast cancer (BC) undergoing chemotherapy.
Forty adult women with BC who underwent anthracycline-based chemotherapy were randomly allocated to the exercise group ( = 21) or the control group ( = 19). Both groups received standard health education and oncology care. In addition, the exercise group wore wearable devices to engage in moderate to high-intensity (50-90% HRmax) aerobic exercise during chemotherapy, while the control group did not carry out exercise intervention. Health-related physical fitness level, physical activity energy expenditure (PAEE), anxiety and depression scores, sleep quality, cancer-related fatigue, and overall quality of life (QoL), were assessed both before (prior to the first chemotherapy session) and after (prior to the fifth chemotherapy session) the exercise intervention. Exercise-related adverse events, exercise compliance, number and severity of gastrointestinal reactions and myelosuppression occurred were recorded during the exercise intervention.
After the intervention, compared to the control group, the exercise group (1) had significantly higher relative VOpeak ( = 0.003) and handgrip strength ( < 0.001); (2) had significantly higher PAEE ( < 0.001); (3) had a significantly lower scores in anxiety ( = 0.007), depression ( = 0.028), sleep quality in domains of subjective sleep quality ( = 0.010), sleep disturbances ( = 0.004), daytime dysfunction ( = 0.007), cancer-related fatigue in domains of physical ( < 0.001) and affective ( < 0.001); and (4) had a significantly lower scores in QoL in domains of physical well-being ( < 0.001) and emotional well-being ( = 0.019), while a significantly higher scores in functional well-being ( < 0.001). Patients in the exercise group experienced less severe gastrointestinal reactions ( = 0.028) and myelosuppressive symptoms ( < 0.001) than that in the control group. Patients in the exercise group had no serious exercise-related adverse events, with a mean exercise adherence of 81.8%.
Wearable device-based aerobic exercise during chemotherapy can be an effective adjunctive therapy to improve physical and mental health in BC patients.
https://www.chictr.org.cn/showproj.html?proj=200247, Identifier: ChiCTR2300073667.
评估基于可穿戴设备的有氧运动对接受蒽环类药物化疗的乳腺癌（BC）女性身心健康的影响。
将 40 名接受基于蒽环类药物化疗的成年 BC 女性随机分配到运动组（n=21）或对照组（n=19）。两组均接受标准健康教育和肿瘤学护理。此外，运动组在化疗期间佩戴可穿戴设备进行中等到高强度（50-90% HRmax）有氧运动，而对照组不进行运动干预。在运动干预前后（第一次化疗前和第五次化疗前）评估健康相关身体适应性水平、身体活动能量消耗（PAEE）、焦虑和抑郁评分、睡眠质量、癌症相关疲劳和整体生活质量（QoL）。在运动干预期间记录运动相关不良事件、运动依从性、胃肠道反应和骨髓抑制的发生次数和严重程度。
干预后，与对照组相比，运动组（1）相对 VOpeak 显著更高（ =0.003），握力显著更强（<0.001）；（2）PAEE 显著更高（<0.001）；（3）焦虑评分显著更低（ =0.007），抑郁评分显著更低（ =0.028），主观睡眠质量（ =0.010）、睡眠障碍（ =0.004）、白天功能障碍（ =0.007）、身体相关的癌症相关疲劳（<0.001）和情感相关的癌症相关疲劳（<0.001）；（4）身体幸福感（<0.001）和情感幸福感（ =0.019）维度的 QoL 评分显著降低，功能幸福感维度的 QoL 评分显著升高（<0.001）。运动组患者胃肠道反应（ =0.028）和骨髓抑制症状（<0.001）较轻。运动组患者无严重运动相关不良事件，平均运动依从率为 81.8%。
化疗期间基于可穿戴设备的有氧运动可以作为一种有效的辅助治疗方法，改善乳腺癌患者的身心健康。
https://www.chictr.org.cn/showproj.html?proj=200247，标识符：ChiCTR2300073667。
