Ren Qingquan, Li Shuyin, Xiao Chunling, Zhang Jiazhi, Lin Hong, Wang Shuai
Department of Labor and Environmental Hygiene, Shenyang Medical College, Liaoning 110034, P.R. China.
Key Laboratory of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Iran J Public Health. 2020 Aug;49(8):1476-1484. doi: 10.18502/ijph.v49i8.3891.
The aim of this study was to investigate the overall impact of PM, PM, NO, SO, CO, and O on the admission of cardiovascular and cerebrovascular disease.
We collected data on cardiovascular and cerebrovascular disease admissions from two hospitals in Shenyang Liaoning, China from Jan 2014 to Dec 2017, as well as daily measurements of six pollutants at 11 sites in Shenyang. The generalized additive model was used to assess the association between daily contaminants and admission to cardiovascular and cerebrovascular disease.
The single-contamination model showed a significant correlation between NO, O, PM and cardiovascular and cerebrovascular diseases at lag0 day. Air pollutants had lag effects on different gender groups. Excess relative risks (ERs) associated with a 10 μg/m increase were 1.522(1.057, 1.988) on lag02 for NO, 0.547% (0.367%, 0.728%), 0.133% (0.061%, 0.205%) on lag3 for O and PM. The dual pollutant model showed that the effects of NO, O, and PM after adjusting the influence of other pollutants were still statistically significant.
Short-term exposure to ambient air pollution (NO, O, and PM) may be associated with an increased risk of daily cardiovascular and cerebrovascular admission, which may provide reliable evidence for further understanding of the potential adverse effects of air pollution on cardiovascular and cerebrovascular diseases.
本研究旨在调查颗粒物（PM）、二氧化氮（NO）、二氧化硫（SO）、一氧化碳（CO）和臭氧（O）对心血管和脑血管疾病入院率的总体影响。
我们收集了2014年1月至2017年12月中国辽宁省沈阳市两家医院心血管和脑血管疾病入院数据，以及沈阳市11个监测点六种污染物的每日监测数据。采用广义相加模型评估每日污染物与心血管和脑血管疾病入院率之间的关联。
单污染物模型显示，在滞后0天，NO、O和PM与心血管和脑血管疾病之间存在显著相关性。空气污染物对不同性别组有滞后效应。与10μg/m增加相关的超额相对风险（ERs），NO在滞后0-2天为1.522（1.057，1.988），O和PM在滞后3天分别为0.547%（0.367%，0.728%）、0.133%（0.061%，0.205%）。双污染物模型显示，在调整其他污染物影响后，NO、O和PM的影响仍具有统计学意义。
短期暴露于环境空气污染（NO、O和PM）可能与每日心血管和脑血管疾病入院风险增加有关，这可能为进一步了解空气污染对心血管和脑血管疾病的潜在不良影响提供可靠证据。
