Zhao Jian-Nan, Fan Ying, Wu Shuo-Dong
Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.
World J Clin Cases. 2020 Oct 6;8(19):4303-4310. doi: 10.12998/wjcc.v8.i19.4303.
In December 2019, an outbreak of unexplained pneumonia was reported in Wuhan, China. The World Health Organization officially named this disease as novel coronavirus disease 2019 (COVID-19). Liver injury was observed in patients with COVID-19, and its severity varied depending on disease severity, geographical area, and patient age. Systemic inflammatory response, immune damage, ischemia-reperfusion injury, viral direct damage, drug induce, mechanical ventilation, and underlying diseases may contribute to liver injury. Although, in most cases, mild liver dysfunction is observed, which is usually temporary and does not require special treatment, the importance of monitoring liver injury should be emphasized for doctors. The risk of COVID-19 infection of liver transplantation recipients caused more and more concerns. In this article, we aimed to review the available literature on liver injury in COVID-19 to highlight the importance of monitoring and treating liver injury in COVID-19.
2019年12月，中国武汉报告了一起不明原因肺炎疫情。世界卫生组织将这种疾病正式命名为2019新型冠状病毒病（COVID-19）。COVID-19患者中观察到肝损伤，其严重程度因疾病严重程度、地理区域和患者年龄而异。全身炎症反应、免疫损伤、缺血再灌注损伤、病毒直接损伤、药物诱导、机械通气和基础疾病可能导致肝损伤。虽然在大多数情况下观察到的是轻度肝功能障碍，通常是暂时的，不需要特殊治疗，但医生应强调监测肝损伤的重要性。肝移植受者感染COVID-19的风险引起了越来越多的关注。在本文中，我们旨在综述关于COVID-19肝损伤的现有文献，以强调监测和治疗COVID-19肝损伤的重要性。
