Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Biomed Res Int. 2020 Oct 5;2020:2580795. doi: 10.1155/2020/2580795. eCollection 2020.
To sort out the literature related to conjunctival bacteria and summarize research hotspots and trends of this field.
The relevant literature data from 1900 to 2019 was retrieved from the Web of Science Core Collection database. After manual selection, each document record includes title, author, keywords, abstract, year, organization, and citation. We imported the downloaded data into CiteSpace V (version 5.5R2) to draw the knowledge map and conduct cooperative network analysis, discipline and journal analysis, cluster analysis, and burst keyword analysis.
After manual screening, there were 285 relevant papers published in the last 28 years (from 1991 to 2019), and the number is increasing year by year. The publications of conjunctival bacteria were dedicated by 1381 authors of 451 institutions in 56 countries/regions. The United States dominates this field (82 literatures), followed by Germany (23 literatures) and Japan (23 literatures). Overall, most cited papers were published with a focus on molecular biology, genetics, nursing, and toxicology. Most papers fall into the category of ophthalmology, veterinary sciences, and pharmacology and pharmacy. The only organized cluster is the "postantibiotic effect," and the top 5 keywords with the strongest citation bursts include "postoperative endophthalmiti(s)," "infectious keratoconjunctiviti(s)," "conjunctiviti(s)," "resistance," and "diversity".
The global field of conjunctival bacteria has expanded in the last 28 years. The United States contributes most. However, there are little cooperation among authors and institutions. Overall, this bibliometric study organized one cluster, "postantibiotic effect", and identified the top 5 hotspots in conjunctival bacteria research: "postoperative endophthalmiti(s)," "infectious keratoconjunctiviti(s)," "conjunctiviti(s)," "resistance," and "diversity". Thus, further research focuses on these topics that may be more helpful to prevent ocular infection and improve prophylaxis strategies to bring a benefit to patients in the near future.
梳理结膜细菌相关文献，总结该领域研究热点和趋势。
从 Web of Science 核心合集数据库中检索了 1900 年至 2019 年的相关文献数据。经过人工筛选，每个文献记录包括标题、作者、关键词、摘要、年份、组织和引文。我们将下载的数据导入 CiteSpace V（版本 5.5R2），绘制知识图谱，并进行合作网络分析、学科和期刊分析、聚类分析和突发关键词分析。
经过人工筛选，近 28 年来（1991 年至 2019 年）共发表了 285 篇相关论文，且数量逐年增加。结膜细菌的出版物由来自 56 个国家/地区的 451 个机构的 1381 位作者撰写。美国在该领域占据主导地位（82 篇文献），其次是德国（23 篇文献）和日本（23 篇文献）。总体而言，被引频次最高的论文主要发表在分子生物学、遗传学、护理和毒理学领域。大多数论文属于眼科学、兽医科学和药理学与药学范畴。唯一的有组织集群是“抗生素后效应”，引用爆发最强的前 5 个关键词包括“术后眼内炎”、“感染性角膜结膜炎”、“结膜炎”、“耐药性”和“多样性”。
过去 28 年来，全球结膜细菌领域不断扩大，美国贡献最大。然而，作者和机构之间的合作很少。总体而言，这项文献计量研究组织了一个集群，即“抗生素后效应”，并确定了结膜细菌研究的前 5 个热点：“术后眼内炎”、“感染性角膜结膜炎”、“结膜炎”、“耐药性”和“多样性”。因此，进一步研究这些可能有助于预防眼部感染和改善预防策略的主题，可能会在不久的将来对患者有所帮助。
