School of Public Health, Nantong University, No. 9 Seyuan Road, Nantong, Jiangsu Province 226000, China.
Nantong Centre for Disease Control and Prevention, No. 189 Gongnong Road, Nantong, Jiangsu Province 226000, China.
Biomed Res Int. 2020 Oct 5;2020:5740654. doi: 10.1155/2020/5740654. eCollection 2020.
Voluntary counseling and testing (VCT) service plays an essential part in the prevention of human immunodeficiency virus (HIV) infection. The purpose of this study was to investigate the characteristics of participants and analyze the major factors of HIV infection in VCT in Nantong, China. This study was conducted between January 2010 and December 2015, based on the responses to questionnaires and blood test results retrieved from the Chinese National HIV/AIDS Comprehensive Control Information System (CNHCCIS). Multivariate logistic regression analyses were used to identify factors related to HIV infection. Differences between first-time testers and repeat testers were assessed using the chi-squared or Fisher test. Over six years, a total of 11,560 VCT participants were included, and 420 cases were confirmed to be HIV-positive. Overall, the annual number of participants was relatively stable with a mean of 1927, while there was a rapid increase in the HIV detection rate (from 1.03% in 2010 to 7.52% in 2015). In multivariate analysis, referral counseling and having a HIV-positive spouse/fixed sex partners were found to be significantly associated with HIV infection among all participants, while being unmarried or divorced, having commercial heterosexual behaviors, and male-male sexual behaviors are additional HIV-related factors for males. Compared to first-time testers, repeat testers were more willing to engage in high-risk sexual behaviors and had higher HIV detection rates ( < 0.001). In conclusion, the HIV epidemic in Nantong is still not controlled. Therefore, in the future, it is critical to expand VCT services to increase the detection rate of HIV, which can prevent the transmission of HIV effectively.
自愿咨询检测（VCT）服务在预防人类免疫缺陷病毒（HIV）感染中起着至关重要的作用。本研究旨在调查参与者的特征，并分析中国南通 VCT 中 HIV 感染的主要因素。本研究基于中国国家艾滋病综合防治信息系统（CNHCCIS）中检索到的问卷回答和血液检测结果，于 2010 年 1 月至 2015 年 12 月期间进行。采用多变量逻辑回归分析来确定与 HIV 感染相关的因素。使用卡方或 Fisher 检验评估首次检测者和重复检测者之间的差异。六年来，共纳入 11560 名 VCT 参与者，其中 420 例被确认为 HIV 阳性。总体而言，参与者的年数量相对稳定，平均为 1927 人，而 HIV 检测率呈快速上升趋势（从 2010 年的 1.03%上升到 2015 年的 7.52%）。多变量分析发现，转诊咨询和 HIV 阳性配偶/固定性伴侣与所有参与者的 HIV 感染显著相关，而未婚或离婚、商业异性性行为和男男性行为是男性 HIV 相关因素。与首次检测者相比，重复检测者更愿意从事高危性行为，HIV 检测率更高（<0.001）。总之，南通的 HIV 流行仍未得到控制。因此，在未来，扩大 VCT 服务以提高 HIV 检测率至关重要，这可以有效预防 HIV 的传播。
