Cardiovascular Sciences Postgraduate Program-Federal Fluminense University, Niterói, RJ, Brazil.
Biomedical Sciences (Physiology) Postgraduate Program-Federal Fluminense University, Niterói, Rio de Janeiro, Brazil.
Eur J Nutr. 2021 Mar;60(2):559-579. doi: 10.1007/s00394-020-02410-1. Epub 2020 Oct 21.
The new coronavirus pandemic is affecting the entire world with more than 25 million confirmed cases in August 2020 according to the World Health Organization. It is known that the virus can affect several tissues and can progress to a respiratory failure in severe cases. To prevent the progression to this stage of the disease and minimize all the damage caused by coronavirus (SARS-CoV-2) the immune system must be in its integrity. A healthy nutritional status are fundamental to efficient immunological protection and consequently a good response to SARS-CoV-2. Micronutrients and bioactive compounds perform functions in immune cells that are extremely essential to stop SARS-CoV-2. Their adequate consumption is part of a non-pharmacological intervention to keep the immune system functioning. This review has as main objective to inform how micronutrients and bioactive compounds could act in the essential immunological pathways could stop SARS-CoV-2, focusing on the functions that have already established in the literature and transposing to this scenario.
根据世界卫生组织的数据，截至 2020 年 8 月，新型冠状病毒大流行已影响全球超过 2500 万人。已知该病毒可影响多种组织，并可在严重情况下进展为呼吸衰竭。为了防止疾病发展到这一阶段，并最大限度地减少冠状病毒（SARS-CoV-2）造成的所有损害，免疫系统必须保持完整。健康的营养状况是有效免疫保护的基础，因此也是对 SARS-CoV-2 产生良好反应的基础。微量营养素和生物活性化合物在免疫细胞中发挥作用，对阻止 SARS-CoV-2 极为重要。它们的充足摄入是保持免疫系统正常运作的非药物干预措施的一部分。这篇综述的主要目的是告知微量营养素和生物活性化合物如何在基本的免疫途径中发挥作用以阻止 SARS-CoV-2，重点介绍文献中已经确立的功能，并将其转化为这一情况。
