Department of Pharmacology, Central University of Punjab, Ghudda-151401, Bathinda, Punjab, India.
Department of Pharmacology and Toxicology, University of Genoa, Genoa, Italy.
Inflammopharmacology. 2021 Aug;29(4):1001-1016. doi: 10.1007/s10787-021-00826-7. Epub 2021 Jun 10.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) known as coronavirus disease (COVID-19), emerged in Wuhan, China, in December 2019. On March 11, 2020, it was declared a global pandemic. As the world grapples with COVID-19 and the paucity of clinically meaningful therapies, attention has been shifted to modalities that may aid in immune system strengthening. Taking into consideration that the COVID-19 infection strongly affects the immune system via multiple inflammatory responses, pharmaceutical companies are working to develop targeted drugs and vaccines against SARS-CoV-2 COVID-19. A balanced nutritional diet may play an essential role in maintaining general wellbeing by controlling chronic infectious diseases. A balanced diet including vitamin A, B, C, D, E, and K, and some micronutrients such as zinc, sodium, potassium, calcium, chloride, and phosphorus may be beneficial in various infectious diseases. This study aimed to discuss and present recent data regarding the role of vitamins and minerals in the treatment of COVID-19. A deficiency of these vitamins and minerals in the plasma concentration may lead to a reduction in the good performance of the immune system, which is one of the constituents that lead to a poor immune state. This is a narrative review concerning the features of the COVID-19 and data related to the usage of vitamins and minerals as preventive measures to decrease the morbidity and mortality rate in patients with COVID-19.
严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)又称冠状病毒病(COVID-19),于 2019 年 12 月在中国武汉出现。2020 年 3 月 11 日,它被宣布为全球大流行。随着世界应对 COVID-19 和缺乏具有临床意义的治疗方法,人们的注意力转向了可能有助于增强免疫系统的方法。考虑到 COVID-19 感染通过多种炎症反应强烈影响免疫系统,制药公司正在努力开发针对 SARS-CoV-2 COVID-19 的靶向药物和疫苗。均衡的营养饮食通过控制慢性传染病,可能在维持整体健康方面发挥重要作用。富含维生素 A、B、C、D、E 和 K 以及一些微量元素如锌、钠、钾、钙、氯和磷的均衡饮食可能对各种传染病有益。本研究旨在讨论和介绍维生素和矿物质在治疗 COVID-19 中的作用的最新数据。血浆浓度中这些维生素和矿物质的缺乏可能导致免疫系统的良好性能下降,这是导致免疫状态不佳的因素之一。这是一篇关于 COVID-19 特征和维生素及矿物质使用数据的叙述性综述,作为预防措施,以降低 COVID-19 患者的发病率和死亡率。