Department of Imaging Center, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, No. 100 Hong Kong Road, Jiang'an District, Wuhan, 430000, China.
Institute of Women and Children's Healthcare, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, No. 100 Hong Kong Road, Jiang'an District, Wuhan, 430000, China.
Pediatr Radiol. 2021 Feb;51(2):222-230. doi: 10.1007/s00247-020-04826-7. Epub 2020 Oct 21.
Chest computed tomography (CT) findings in children with coronavirus disease 2019 (COVID-19) have been rarely reported in a comprehensive and systematic manner.
We investigated the chest CT findings in children with COVID-19, and explored the differences in these findings between symptomatic patients and asymptomatic patients.
Demographic findings, clinical characteristics, duration of hospital stay and viral shedding, and chest CT findings in 201 children infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) were retrospectively analyzed from January 15 to March 20, 2020, and divided into two groups: symptomatic group (n=136) and asymptomatic group (n=65). Chi-square test and Student's t-test were used for statistical analysis.
Symptomatic patients were mainly young children ≤3 years old (54/63, 86%),while asymptomatic patients were mainly children ≥ 6 years old (51/111, 46%). Fever (41%) and cough (41%) were the most common symptoms. Overall, 119/201 (59%) patients had chest CT findings, and symptomatic patients accounted for 82% (98/119). The CT findings presented as bilateral multiple lesions (60/119, 50.4%), ground-glass opacities (83/119, 70%) and/or consolidation (44/119, 37%) with a peripheral and subpleural distribution (62/83, 75%). Fifteen of 87 (7.2%) patients with lung lesions showed complete lesion absorption, and 42/87 (48%) improved within a mean of 9.1 (standard deviation [SD] 3.2) days. The mean duration of viral shedding was 8.7 (SD 4.9) days. Pleural effusion was very rare. No lymphadenopathy was found in either group.
Symptoms associated with pulmonary involvement were most common in infants and young children. The lung lesions of most patients were absorbed and improved in about 9 days.
儿童 2019 年冠状病毒病（COVID-19）的胸部计算机断层扫描（CT）表现很少有全面系统的报道。
探讨儿童 COVID-19 的胸部 CT 表现，并比较有症状与无症状患者之间的 CT 表现差异。
回顾性分析 2020 年 1 月 15 日至 3 月 20 日期间 201 例严重急性呼吸综合征冠状病毒-2（SARS-CoV-2）感染患儿的临床资料，包括人口统计学资料、临床特征、住院时间、病毒脱落情况及胸部 CT 表现。根据是否有症状将患儿分为有症状组（n=136）和无症状组（n=65）。采用卡方检验和 t 检验进行统计学分析。
有症状患儿主要为≤3 岁的婴幼儿（54/63，86%），无症状患儿主要为≥6 岁的儿童（51/111，46%）。最常见的症状为发热（41%）和咳嗽（41%）。201 例患儿中，119 例（59%）有胸部 CT 表现，其中有症状患儿占 82%（98/119）。CT 表现为双侧多发斑片状影（60/119，50.4%）、磨玻璃影（83/119，70%）和/或实变影（44/119，37%），多分布于外周和胸膜下（62/83，75%）。87 例肺部病变患儿中，15 例（7.2%）完全吸收，42 例（48%）在平均 9.1（标准差 3.2）天内改善。病毒脱落平均持续 8.7（标准差 4.9）天。胸腔积液少见。两组均未见淋巴结肿大。
与肺部受累相关的症状在婴幼儿中最为常见。大多数患儿的肺部病变在 9 天左右吸收和改善。
