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膳食中丙烯酰胺的暴露及对韩国人口的相关健康风险。

Dietary Exposure to Acrylamide and Associated Health Risks for the Korean Population.

机构信息

Research Group of Natural Materials and Metabolism, Korea Food Research Institute, Wanju-gun 55365, Korea.

Research Group of Consumer Safety, Korea Food Research Institute, Wanju-gun 55365, Korea.

出版信息

Int J Environ Res Public Health. 2020 Oct 19;17(20):7619. doi: 10.3390/ijerph17207619.

Abstract

The aim of the study was to estimate the dietary exposure to acrylamide (AA) from the consumption of various processed food and to assess the associated health risks in different age groups in Korea. Potato crisps and French fries presented the highest mean levels of AA (546 and 372 μg/kg, respectively) followed by coffee (353 μg/kg) and tea products (245 μg/kg). The mean AA dietary exposure values for toddlers (≤2 years), children (3-6 years), children (7-12 years), adolescents (13-19 years), adults (20-64 years), and seniors (≥65 years) were estimated to be 0.15, 0.13, 0.06, 0.06, 0.08, and 0.06 μg/kg body weight (BW)/day, respectively. Based on the benchmark dose lower confidence limit (BMDL) of 0.18 and 0.31 mg/kg BW/day, the calculated mean and 95th percentile values for the margin of exposure were below 10,000 for the all age groups suggesting possible health concern for Koreans. Biscuits, crisps, and coffee were the primary foods contributing to dietary AA exposure among these in the Korean populations. In children, considering the health risk of AA dietary exposure, especially from biscuits and crisps, there is a need to further control and modify dietary habits to ensure lower AA exposure.

摘要

本研究旨在评估韩国不同年龄段人群通过食用各种加工食品摄入丙烯酰胺(AA)的情况,并评估其相关健康风险。薯片中 AA 的平均含量最高(分别为 546μg/kg 和 372μg/kg),其次是咖啡(353μg/kg)和茶产品(245μg/kg)。幼儿(≤2 岁)、儿童(3-6 岁)、儿童(7-12 岁)、青少年(13-19 岁)、成年人(20-64 岁)和老年人(≥65 岁)的 AA 膳食暴露平均值估计值分别为 0.15μg/kg 体重/天、0.13μg/kg 体重/天、0.06μg/kg 体重/天、0.06μg/kg 体重/天、0.08μg/kg 体重/天和 0.06μg/kg 体重/天。基于 0.18mg/kg BW/天和 0.31mg/kg BW/天的基准剂量下限(BMDL),所有年龄段的暴露边际的计算平均值和 95 百分位值均低于 10,000,表明韩国人可能存在健康风险。饼干、薯片和咖啡是这些韩国人群中 AA 膳食暴露的主要食物来源。对于儿童,考虑到 AA 膳食暴露的健康风险,特别是来自饼干和薯片的风险,需要进一步控制和改变饮食习惯,以确保较低的 AA 暴露。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3746/7589863/cb192566d7dc/ijerph-17-07619-g001.jpg

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