Malcová H, Dallos T, Bouchalova K, Brejchová I, Brichová M, Bušányová B, Fabianová J, Fráňová J, Furdová A, Jarošová K, Kobrová K, Kostolná B, Košková E, Lokaj M, Macků M, Melocíková J, Michaličková M, Minxová L, Moravčíková D, Němcová D, Pískovský T, Říhová E, Schüller M, Skalická E, Svozílková P, Tomčíková D, Vargová V, Vrtíková E, Doležalová P, Heissigerová J
Cesk Slov Oftalmol. 2020 Fall;76(4):1-15. doi: 10.31348/2020/7.
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and uveitis is its most important extra-articular manifestation. Evidence-based recommendations are available only to a limited extent and therefore JIA associated uveitis management is mostly based on physicians experience. Consequently, treatment practices differ widely, both nationally and internationally. Therefore, an effort to optimize and publish recommendations for the care of children and young adults with rheumatic diseases was launched in 2012 as part of the international project SHARE (Single Hub and Access Point for Pediatric Rheumatology in Europe) to facilitate clinical practice for paediatricians and (paediatric) rheumatologists. The aim of this work was to translate published international SHARE recommendations for the diagnosis and treatment of JIA associated uveitis and to adapt them for use in the Czech and Slovak Republics. International recommendations were developed according to the standard methodology of the European League against Rheumatism (EULAR) by a group of nine experienced paediatric rheumatologists and three experts in ophthalmology. It was based on a systematic literature review and evaluated in the form of an online survey and subsequently discussed using a nominal group technique. Recommendations were accepted if > 80% agreement was reached (including all three ophthalmologists). A total of 22 SHARE recommendations were accepted: 3 on diagnosis, 5 on disease activity assessment, 12 on treatment and 2 on future recommendations. Translation of the original text was updated and modified with data specific to the czech and slovak health care systems and supplemented with a proposal for a protocol of ophthalmological dispensarization of paediatric JIA patients and a treatment algorithm for JIA associated uveitis. Conclusion: The aim of the SHARE initiative is to improve and standardize care for paediatric patients with rheumatic diseases across Europe. Therefore, recommendations for the diagnosis and treatment of JIA-associated uveitis have been formulated based on the evidence and agreement of leading European experts in this field.
幼年特发性关节炎（JIA）是儿童中最常见的风湿性疾病，葡萄膜炎是其最重要的关节外表现。循证推荐在很大程度上有限，因此JIA相关葡萄膜炎的管理大多基于医生的经验。因此，治疗方法在国内和国际上差异很大。因此，作为国际项目SHARE（欧洲儿科风湿病单一中心和接入点）的一部分，2012年发起了一项为患有风湿性疾病的儿童和年轻人优化并发布护理建议的工作，以促进儿科医生和（儿科）风湿病学家的临床实践。这项工作的目的是翻译已发表的国际SHARE关于JIA相关葡萄膜炎诊断和治疗的建议，并使其适用于捷克共和国和斯洛伐克共和国。国际建议由九名经验丰富的儿科风湿病学家和三名眼科专家根据欧洲抗风湿病联盟（EULAR）的标准方法制定。它基于系统的文献综述，并以在线调查的形式进行评估，随后使用名义群体技术进行讨论。如果达成>80%的共识（包括所有三名眼科医生），则建议被接受。总共接受了22条SHARE建议：3条关于诊断，5条关于疾病活动评估，12条关于治疗，2条关于未来建议。原始文本的翻译根据捷克和斯洛伐克医疗保健系统的特定数据进行了更新和修改，并补充了一份针对儿科JIA患者眼科诊疗方案的建议以及JIA相关葡萄膜炎的治疗算法。结论：SHARE倡议的目的是改善和规范欧洲儿科风湿性疾病患者的护理。因此，基于该领域欧洲领先专家的证据和共识，制定了JIA相关葡萄膜炎的诊断和治疗建议。
