Schön Klinik Hamburg Eilbek, Hamburg, Germany.
Meyer Children's Hospital, University of Florence, Florence, Italy.
Arthritis Care Res (Hoboken). 2023 May;75(5):975-982. doi: 10.1002/acr.24963. Epub 2023 Jan 10.
The Multinational Interdisciplinary Working Group for Uveitis in Childhood identified the need to update the current guidelines, and the objective here was to produce this document to guide clinicians managing children with juvenile idiopathic arthritis-associated uveitis (JIAU) and idiopathic chronic anterior uveitis (CAU).
The group analyzed the literature published between December 2014 and June 2020 after a systematic literature review conducted by 2 clinicians. Pediatric rheumatologists were paired with ophthalmologists to review the eligible 37 publications. The search criteria were selected to reflect those used for the 2018 Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) recommendations, in order to provide an update, rather than a replacement for that publication. The summary of the current evidence for each SHARE recommendation was presented to the expert committee. These recommendations were then discussed and revised during a video consensus meeting on January 22, 2021, with 14 voting participants, using a nominal group technique to reach consensus.
JIAU treatment was extended to include CAU. Fourteen recommendations regarding treatment of JIAU und CAU with >90% agreement were accepted.
An update to the previous 2018 SHARE recommendations for the treatment of children with JIAU with the addition of CAU was created using an evidence-based consensus process. This guideline should help support clinicians to care for children and young people with CAU.
多国儿科学多学科工作组（Multinational Interdisciplinary Working Group for Uveitis in Childhood）确定需要更新当前的指南，本研究的目的是制定本文件，以指导管理儿童幼年特发性关节炎相关葡萄膜炎（juvenile idiopathic arthritis-associated uveitis，JIAU）和特发性慢性前葡萄膜炎（idiopathic chronic anterior uveitis，CAU）的临床医生。
该工作组对 2 位临床医生进行系统文献回顾后，于 2014 年 12 月至 2020 年 6 月期间对文献进行了分析。小儿风湿病专家与眼科医生合作，对 37 篇符合条件的文献进行了审查。该搜索标准的选择反映了 2018 年欧洲儿科风湿病单一枢纽和接入点（Single Hub and Access point for pediatric Rheumatology in Europe，SHARE）建议中使用的标准，以便提供更新，而不是替代该出版物。每位专家委员会成员都提交了当前证据摘要，以用于 SHARE 推荐。2021 年 1 月 22 日，通过视频共识会议讨论和修订了这些建议，14 名有投票权的参与者使用名义小组技术达成共识。
将 JIAU 的治疗方法扩展到 CAU。接受了 14 项针对 JIAU 和 CAU 治疗的建议，这些建议获得了超过 90%的共识。
使用循证共识过程更新了 2018 年 SHARE 推荐治疗 JIAU 儿童的指南，增加了 CAU。该指南应有助于支持临床医生为 CAU 患儿和青少年提供护理。
