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成人艾滋病毒感染者在接受抗逆转录病毒治疗诊所中经历的疲劳及其相关因素:埃塞俄比亚一项基于医院的横断面研究。

Experience of fatigue and associated factors among adult people living with HIV attending ART clinic: a hospital-based cross-sectional study in Ethiopia.

机构信息

Department of Physiotherapy, School of Medicine, College of Medicine and Health Sciences, and Specialized Hospital, Gondar, Amhara, Ethiopia.

Department of Physiotherapy, School of Medicine, College of Health Sciences and Ayder Comprehensive Specialized Hospital, Mekelle University, Mekelle, Tigray, Ethiopia.

出版信息

BMJ Open. 2020 Oct 21;10(10):e042029. doi: 10.1136/bmjopen-2020-042029.

DOI:10.1136/bmjopen-2020-042029
PMID:33087381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7580062/
Abstract

OBJECTIVE

This study aimed to determine the prevalence of fatigue and the factors associated among adult people living with HIV attending antiretroviral therapy clinic in Gondar town, Ethiopia.

DESIGN

Cross-sectional.

SETTING

Governmental health facility that provides HIV care in Gondar town.

OUTCOME MEASURE

Fatigue is defined by nine items version Fatigue Severity Scale.

PARTICIPANTS

Adult (aged 18 and above) people living with HIV in Gondar town (n=392).

RESULT

A total of 408 HIV seropositive adults were approached for consent, among which 392 participants consented to participate in this study, with a response rate of 96.1%. The mean age of the participants was 40.5±8.5 years. The prevalence of HIV-related fatigue was 53.3% and about 66% of women living with HIV experienced fatigue. The factors associated with fatigue experience were; female gender (adjusted OR (AOR): 2.61, 95% CI 1.01 to 5.3), being married (AOR: 0.18, 95% CI 0.10 to 0.9), low income (AOR: 7.1, 95% CI 4.6 to 22.15), unemployed (AOR: 2.79, 95% CI 1.19 to 9.84), parity (AOR: 4.87, 95% CI 2.18 to 17.9), being anaemic (AOR: 12.45, 95% CI 5.6 to 41.01), depression (AOR: 4.51, 95% CI 1.91 to 11.20), mild weight loss (AOR: 4.2 95% CI 2.56 to 13.9) and moderate weight loss (AOR: 5.1, 95% CI 1.85 to 16.12), respectively.

CONCLUSION

The findings of this study revealed that experiencing fatigue is quite common among adult people living with HIV. It is important for the healthcare professionals and people living with HIV to understand; the possible causes of fatigue, remedies and ways to reclaim energy. The predisposing factors and complications that cause fatigue should be aggressively diagnosed and treated by the clinicians. Further qualitative studies exploring the reasons for experiencing HIV-related fatigue might help designing interventions.

摘要

目的

本研究旨在确定在埃塞俄比亚贡德尔镇接受抗逆转录病毒疗法的成年艾滋病毒感染者中疲劳的流行情况及其相关因素。

设计

横断面研究。

地点

为贡德尔镇提供艾滋病毒护理的政府卫生机构。

结果测量

疲劳由九项疲劳严重程度量表定义。

参与者

贡德尔镇(n=392)年龄在 18 岁及以上的成年艾滋病毒感染者。

结果

共有 408 名艾滋病毒阳性成年人被征求同意,其中 392 名参与者同意参加这项研究,应答率为 96.1%。参与者的平均年龄为 40.5±8.5 岁。艾滋病毒相关疲劳的患病率为 53.3%,约 66%的女性艾滋病毒感染者经历了疲劳。与疲劳体验相关的因素包括:女性(调整后的比值比(OR):2.61,95%置信区间(CI)为 1.01 至 5.3)、已婚(OR:0.18,95%CI 0.10 至 0.9)、低收入(OR:7.1,95%CI 4.6 至 22.15)、失业(OR:2.79,95%CI 1.19 至 9.84)、产次(OR:4.87,95%CI 2.18 至 17.9)、贫血(OR:12.45,95%CI 5.6 至 41.01)、抑郁(OR:4.51,95%CI 1.91 至 11.20)、轻度体重减轻(OR:4.2 95%CI 2.56 至 13.9)和中度体重减轻(OR:5.1,95%CI 1.85 至 16.12)。

结论

本研究结果表明,成年艾滋病毒感染者中疲劳的发生率相当高。卫生保健专业人员和艾滋病毒感染者了解疲劳的可能原因、补救措施和恢复能量的方法非常重要。临床医生应积极诊断和治疗导致疲劳的诱发因素和并发症。进一步进行定性研究,探索艾滋病毒相关疲劳的原因,可能有助于设计干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2536/7580062/1f116c8628cc/bmjopen-2020-042029f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2536/7580062/1f116c8628cc/bmjopen-2020-042029f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2536/7580062/1f116c8628cc/bmjopen-2020-042029f01.jpg

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