Muzarath S, Nandyal Sonam S, Bindu B J, Murthy C Narayana
Department of Pathology, Basaveshwara Medical College and Hospital, Chitradurga, Karnataka, India.
J Cytol. 2020 Jul-Sep;37(3):131-135. doi: 10.4103/JOC.JOC_159_19. Epub 2020 Jun 30.
Many contaminants are routinely encountered in cytopathology practice. However, because of lack of familiarity and experience with them, many are unnoticed, neglected, or confused with other structures of major relevance.
The purpose of this study was to intentionally introduce contaminants into the smears and to provide distinctive morphological criteria required for the microscopist to identify them confidently to avoid possible confusion.
Prospective cross-sectional study.
This study included smears prepared from the buccal mucosa of healthy volunteers. Common contaminants were deliberately introduced into the smears, fixed using 90% ethanol, and stained with Hematoxylin and Eosin stain (H and E) and Papanicolaou stain (PAP). The study also included smears from leftover cerebrospinal fluid (CSF) and wet mount preparations. The morphology of these contaminants was studied and the results were tabulated.
Nil.
The vivid morphological appearance of these commonly encountered contaminants were described and many of these mimicked structures of major relevance.
Contaminants and mimickers can make the evaluation of cytologic specimens challenging and may necessitate secondary review by another pathologist or further workup. Knowledge and familiarity of these commonly encountered extraneous substances will help to prevent misinterpretation.
在细胞病理学实践中经常会遇到许多污染物。然而，由于对它们缺乏熟悉度和经验，许多污染物未被注意到、被忽视或与其他主要相关结构相混淆。
本研究的目的是有意将污染物引入涂片，并提供显微镜检查人员自信识别它们所需的独特形态学标准，以避免可能的混淆。
前瞻性横断面研究。
本研究包括从健康志愿者颊黏膜制备的涂片。将常见污染物故意引入涂片，用90%乙醇固定，并用苏木精和伊红染色（H&E）以及巴氏染色（PAP）。该研究还包括剩余脑脊液（CSF）涂片和湿片制备。研究这些污染物的形态并将结果列表。
无。
描述了这些常见污染物生动的形态外观，其中许多模仿了主要相关结构。
污染物和类似物会使细胞学标本的评估具有挑战性，可能需要另一位病理学家进行二次检查或进一步检查。了解和熟悉这些常见的外来物质将有助于防止误诊。
