Department of Medical and Surgical Sciences, Unit of Legal Medicine, University of Bologna, via Irnerio, 49, 40126, Bologna, Italy.
Department of Biological, Geological and Environmental Sciences-Lab. of Molecular Anthropology & Centre for Genome Biology, University of Bologna, Via Selmi 3, 40126, Bologna, Italy.
Int J Legal Med. 2021 Mar;135(2):449-453. doi: 10.1007/s00414-020-02446-2. Epub 2020 Oct 22.
Eritrea is a multi-ethnic country of over 3 million of people consisting of different ethnic groups, having each its own language and cultural tradition. Due to the lack of population genetic data for markers of forensic interest, in this study, we analyzed the genetic polymorphisms of 23 Y-chromosome STR loci and of 12 X-chromosome STR loci in a sample of 255 unrelated individuals from 8 Eritrean ethnic groups, with the aim to generate a reference haplotype database for anthropological and forensic applications. X- and Y-chromosomes markers may indeed offer information especially in personal identification and kinship testing, when relying on the availability of large local population data to derive sufficiently accurate frequency estimates. The population genetic analyses in the Eritrean sample for both the two set of Y- and X-STR markers showed high power of discrimination both at country-based and population levels. Comparison population results highlight the importance of considering the ethnic composition within the analyzed country and the necessity of increasing available data especially when referring to heterogeneous populations such as the African ones.
厄立特里亚是一个拥有超过 300 万人口的多民族国家，由不同的民族组成，每个民族都有自己的语言和文化传统。由于缺乏针对法医学标记的人口遗传数据，在这项研究中，我们分析了来自 8 个厄立特里亚民族的 255 名无关个体的 23 个 Y 染色体 STR 位点和 12 个 X 染色体 STR 位点的遗传多态性，旨在为人类学和法医学应用生成参考单体型数据库。X 和 Y 染色体标记确实可以提供信息，特别是在个人识别和亲属关系测试中，当依赖于大型本地人群数据来得出足够准确的频率估计时。对厄立特里亚样本的两个 Y-和 X-STR 标记集的群体遗传分析均显示出在国家和群体水平上均具有较高的鉴别力。比较人群结果强调了在分析国家时考虑民族构成的重要性，以及在涉及如非洲人群等异质人群时增加可用数据的必要性。
