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孕妇和非孕妇的卵巢及外周静脉血中前列腺素F2α水平

Ovarian and peripheral venous blood prostaglandin F2alpha levels in pregnant and nonpregnant women.

作者信息

Walters W A, Greco S, Vijayakumar R, Wood C

出版信息

Int J Gynaecol Obstet. 1978;16(3):259-62. doi: 10.1002/j.1879-3479.1978.tb00439.x.

DOI:10.1002/j.1879-3479.1978.tb00439.x
PMID:33090
Abstract

Prostaglandin F2alpha (PGF2alpha) was measured by radioimmunoassay in human blood plasma collected from both ovarian veins and from a peripheral vein in eight pregnant and seven nonpregnant women. In the pregnant women, significantly higher levels of PGF2alpha were found in venous blood plasma taken from the ovary which contained the corpus luteum than were found in either the ovarian vein blood plasma from the opposite ovary or in the blood plasma from a peripheral vein. Thus, PGF2alpha levels in the venous blood plasma from the ovary without a corpus luteum were not significantly different from those found in the peripheral venous blood plasma. In seven nonpregnant women, significantly higher levels of PGF2alpha were found in the venous blood plasma taken from the ovary which contained a corpus luteum than were found in the blood plasma taken from a peripheral vein. The former levels did not differ significantly from those found in the venous blood plasma taken from the ovary without a corpus luteum in these nonpregnant women. Thus, in nonpregnant women a significant difference was found between PGF2alpha levels in the venous blood plasma from the ovary without a corpus luteum and those in peripheral venous blood plasma.

摘要

采用放射免疫分析法对8名孕妇和7名非孕妇的卵巢静脉血和外周静脉血中的血浆前列腺素F2α(PGF2α)进行了测定。在孕妇中,发现含有黄体的卵巢静脉血浆中PGF2α水平显著高于对侧卵巢静脉血浆或外周静脉血浆中的水平。因此,无黄体卵巢静脉血浆中的PGF2α水平与外周静脉血浆中的水平无显著差异。在7名非孕妇中,发现含有黄体的卵巢静脉血浆中PGF2α水平显著高于外周静脉血浆中的水平。在这些非孕妇中,前者水平与无黄体卵巢静脉血浆中的水平无显著差异。因此,在非孕妇中,发现无黄体卵巢静脉血浆中的PGF2α水平与外周静脉血浆中的水平存在显著差异。

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