Division of Sports and Rehabilitation Medicine, Ulm University, Ulm, Baden-Württemberg, Germany.
PLoS One. 2020 Oct 23;15(10):e0241079. doi: 10.1371/journal.pone.0241079. eCollection 2020.
To evaluate the intra-unit (RELINTRA) and inter-unit reliability (RELINTER) of two structurally identical units of the metabolic analyser K5 (COSMED, Rome, Italy) that allows to utilize either breath-by-breath (BBB) or dynamic mixing chamber (DMC) technology.
Identical flow- and gas-signals were transmitted to both K5s that always operated simultaneously either in BBB- or DMC-mode. To assess RELINTRA and RELINTER, a metabolic simulator was applied to simulate four graded levels of respiration. RELINTRA and RELINTER were expressed as typical error (TE%) and Intraclass Correlation Coefficient (ICC). To assess also inter-unit differences via natural respiratory signals, 12 male athletes performed one incremental bike step test each in BBB- and DMC-mode. Inter-unit differences within biological testing were expressed as percentages.
In BBB, TE% of RELINTRA ranged 0.30-0.67 vs. RELINTER 0.16-1.39 and ICC ranged 0.57-1.00 vs. 0.09-1.00. In DMC, TE% of RELINTRA ranged 0.38-0.90 vs. RELINTER 0.03-0.86 and ICC ranged 0.22-1.00 vs. 0.52-1.00. Mean inter-unit differences ranged -2.30-2.20% (Cohen's ds (ds) 0.13-1.52) for BBB- and -0.55-0.61% (ds 0.00-0.65) for DMC-mode, respectively. Inter-unit differences for [Formula: see text] and RER were significant (p < 0.05) at each step.
Two structurally identical K5-units demonstrated accurate RELINTRA with TE < 2.0% and similar RELINTER during metabolic simulation. During biological testing, inter-unit differences for [Formula: see text] and RER in BBB-mode were higher than 2% with partially large ES in BBB. Hence, the K5 should be allocated personally wherever possible. Otherwise, e.g. in multicenter studies, a decrease in total reliability needs to be considered especially when the BBB-mode is applied.
评估两种结构相同的新陈代谢分析仪 K5 单元（意大利罗马 COSMED 公司）的单元内（RELINTRA）和单元间（RELINTER）可靠性，该仪器可采用逐口气（BBB）或动态混合室（DMC）技术。
将相同的流量和气体信号传输到两个 K5 单元，两个 K5 单元总是同时以 BBB 或 DMC 模式运行。为了评估 RELINTRA 和 RELINTER，使用代谢模拟器来模拟四种不同程度的呼吸。以典型误差（TE%）和组内相关系数（ICC）来表示 RELINTRA 和 RELINTER 的单元内和单元间可靠性。为了通过自然呼吸信号评估单元间差异，12 名男性运动员分别在 BBB 和 DMC 模式下进行一次递增自行车台阶测试。生物学测试中的单元间差异以百分比表示。
在 BBB 模式下，RELINTRA 的 TE%范围为 0.30-0.67，而 RELINTER 的 TE%范围为 0.16-1.39，ICC 范围为 0.57-1.00 与 0.09-1.00。在 DMC 模式下，RELINTRA 的 TE%范围为 0.38-0.90，而 RELINTER 的 TE%范围为 0.03-0.86，ICC 范围为 0.22-1.00 与 0.52-1.00。BBB 模式下的平均单元间差异范围为-2.30-2.20%（Cohen's ds（ds）0.13-1.52），DMC 模式下的平均单元间差异范围为-0.55-0.61%（ds 0.00-0.65）。在每个阶段，[公式：见正文]和 RER 的单元间差异均具有统计学意义（p<0.05）。
在代谢模拟过程中，两种结构相同的 K5 单元具有准确的 RELINTRA，其 TE<2.0%，相似的 RELINTER。在生物学测试中，BBB 模式下的[公式：见正文]和 RER 的单元间差异高于 2%，并且 BBB 模式下的 ES 部分较大。因此，只要可能，就应单独分配 K5。否则，例如在多中心研究中，当应用 BBB 模式时，需要考虑总可靠性的降低。
Zotero 插件
