Department of Health and Welfare, College of City Management, University of Taipei, Taipei, Taiwan.
Division of Chest Medicine, Department of Internal Medicine, Puli Branch of Taichung Veterans General Hospital, Nantou, Taiwan; Central Taiwan University of Science and Technology Department of Eldercare, Taichung, Taiwan.
Nutr Metab Cardiovasc Dis. 2021 Jan 4;31(1):110-118. doi: 10.1016/j.numecd.2020.08.014. Epub 2020 Aug 20.
The nutritional status of the elderly is different from that of young people. Body composition changes as people age, for example, fat mass increases, muscle mass decreases, and body fat distribution is changed. We aimed to investigate the association of body mass index (BMI) with cause-specific mortality in the elderly population.
The data of annual health examination for the older citizens (≥65 years old) from 2006 to 2011 in Taipei City Hospital were used. Information on baseline demographics, lifestyle behaviors, medical, and drug usage were collected by a self-administered questionnaire. Cause-specific mortality was ascertained from the National Registration of Death. Individuals were followed up until death or December 31, 2012, whichever was earlier. Univariable and multivariable Cox proportional hazard analyses were applied to investigate the association between BMI and all-cause mortality. Among 81,221 older people included in the analysis, 42,602 (52.45%) were men. The mean age was 73.85 ± 6.32 years. Among the 81,221 participants, 3398 (4.18%) were underweight, 36,476 (44.91%) were normal weight, 25,708 (31.65%) were overweight, and 15,639 (19.25%) were obese. Those in the BMI category 27 ≤ BMI<28 kg/m had the lowest all-cause mortality risk. The BMI of lowest cause-specific mortality was between 27 kg/m and 28 kg/m in infection mortality, between 28 kg/m and 29 kg/m in circulation mortality, between 29 kg/m and 30 kg/m in respiratory mortality, and between 31 kg/m and 32 kg/m in cancer mortality.
The current study found a J-shaped relation between BMI and cause-specific mortality in the elderly population of Taiwan.
老年人的营养状况与年轻人不同。人体成分会随着年龄的增长而发生变化，例如，脂肪量增加，肌肉量减少，体脂分布发生改变。本研究旨在探讨体质指数（BMI）与老年人特定原因死亡率的关系。
本研究使用了台北市立联合医院 2006 年至 2011 年的老年人年度体检数据。通过自填问卷收集了基线人口统计学、生活方式行为、医疗和药物使用等信息。特定原因死亡率通过国家死亡登记确定。个体随访至死亡或 2012 年 12 月 31 日，以先发生者为准。采用单变量和多变量 Cox 比例风险分析来研究 BMI 与全因死亡率之间的关系。在纳入分析的 81221 名老年人中，42602 名（52.45%）为男性。平均年龄为 73.85±6.32 岁。在 81221 名参与者中，3398 名（4.18%）为体重不足，36476 名（44.91%）为正常体重，25708 名（31.65%）为超重，15639 名（19.25%）为肥胖。BMI 类别为 27≤BMI<28kg/m2 的人群全因死亡率风险最低。感染性死亡率中最低特定原因死亡率的 BMI 为 27kg/m2 至 28kg/m2，循环系统死亡率中最低特定原因死亡率的 BMI 为 28kg/m2 至 29kg/m2，呼吸系统死亡率中最低特定原因死亡率的 BMI 为 29kg/m2 至 30kg/m2，癌症死亡率中最低特定原因死亡率的 BMI 为 31kg/m2 至 32kg/m2。
本研究发现台湾老年人的 BMI 与特定原因死亡率之间呈 J 型关系。
