Research Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Irkutsk State Medical University, Ministry of Health of the Russian Federation, Irkutsk, Russia.
Bull Exp Biol Med. 2020 Oct;169(6):747-750. doi: 10.1007/s10517-020-04970-y. Epub 2020 Oct 24.
Activity of some antioxidant enzymes (superoxide dismutase, catalase, and glutathionedependent enzymes), as well as the level of LPO products in the region regional blood flow (collateral branches of the main trunks of ovarian veins) in women with pelvic venous disorders were studied. A compensatory increase in activity of superoxide dismutase, catalase, and glutathione peroxidase during stage I of the disease was found; during stage II, superoxide dismutase activity decreased and glutathione peroxidase increased, while during stage III, pronounced decrease in activities of all studied enzymes was observed. The level of lipid peroxidation products in the regional blood flow increased as the disease progressed, with maximum values in the third stage.
研究了患有盆腔静脉疾病的女性局部血液流动（卵巢静脉主干的侧支）中某些抗氧化酶（超氧化物歧化酶、过氧化氢酶和谷胱甘肽依赖酶）的活性以及 LPO 产物的水平。在疾病的第一阶段发现超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶的活性代偿性增加；在第二阶段，超氧化物歧化酶活性降低，谷胱甘肽过氧化物酶增加，而在第三阶段，所有研究酶的活性明显降低。随着疾病的进展，局部血液流动中脂质过氧化产物的水平增加，在第三阶段达到最大值。
