School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, PR China.
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, PR China.
J Pharm Biomed Anal. 2021 Jan 5;192:113675. doi: 10.1016/j.jpba.2020.113675. Epub 2020 Oct 10.
Sample preparation such as isolation and pre-concentration is a crucial step for the phytochemical analysis. Magnetic solid-phase extraction (MSPE) has received considerable attention, mainly due to its phase separation more conveniently by facile magnetic decantation as compared to traditional SPE. This review focused on the recent applications of MSPE in sample preparation for the analysis of phytochemical compounds in plants, biological samples and Chinese herbal preparations. In addition, the enzymes immobilized on the magnetic materials and used for the biospecific extraction of enzyme inhibitors were also discussed. The information summarized in this article may provide a reference to the further applications of MSPE in phytochemical analysis.
样品制备，如分离和预浓缩，是植物化学分析的关键步骤。磁性固相萃取（MSPE）受到了相当多的关注，主要是因为与传统 SPE 相比，它更容易通过简便的磁分离进行相分离。本综述主要关注 MSPE 在植物、生物样品和中草药制剂中植物化学化合物分析的样品制备中的最新应用。此外，还讨论了固定在磁性材料上的酶在酶抑制剂的生物特异性提取中的应用。本文总结的信息可能为 MSPE 在植物化学分析中的进一步应用提供参考。
